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Nutrex Lipo 6X vs Lipo 6 Review

What is Lipo 6 by Nutrex?

The fat burner Lipo 6 has become a very popular weight loss supplement. Certainly with a name like that, it could only mean one thing - a diet pill consisting of 6 key active ingredients! Actually that was the case with the older formula, but it isn't the case with the new formulations. With its immense popularity, it only makes sense for Nutrex to capitalize on that popularity and release different versions of this diet pill including Lipo 6X, Black, and For Her versions.

Our review here is for comparing the differences between Lipo 6 vs. Lipo 6X. While they may be from the same line of fat burner made by Nutrex, their ingredients and formulas are quite different, and we'll discuss all of that here.

The "Lipo" in L6 is the prefix meaning lipid or fat, so this would seem like an appropriate enough name for an effective fat burner. The key active ingredients contained in lipo6 include Synephrine, Guggulsterones, Yohimbine, and Caffeine. The key ingredients in Lipo 6X include synephrine, yohimbine, acacia rigidula, caffeine, guggulsterones, Phenylethylamine (PEA), and hordenine. As you can see, these two different versions share a few key active ingredients such as guggulsterones, yohimbe, and synephrine; however, L6X contains several more ingredients, which we'll discuss in a bit.

With all the fancy ingredients aside, the crux of the matter here is: does the Lipo 6 work?

Nutrex Lipo 6x Review & Side Effects

Generally there are 2 parts to the equation, which we base our reviews on: 1) an in depth look at some of the active key ingredients of the fat burner, and 2) the feedbacks and testimonial we receive on various products at our customer reviews section here, where we've received thousands of user reviews on hundreds of products. Lipo 6 fat burner is no different, and has accumulated many user testimonials - some positive, some negative, and some giving a detailed experience account with the diet pill. But more on that later.

The first thing to consider when choosing a fat burner, is its active ingredients, and it is important to understand the functions, benefits and side effects of the individual ingredients in diet pills to be able to make an informed judgment and purchasing decision. Because Lipo 6 and Lipo 6X shares some common ingredients, what we'll do, is discuss these common ingredients first, and then we'll discuss some of the extra ingredients contained in L6X after. Again, the common ingredients shared by the two fat burners are:

  • Synephrine 20mg
  • Guggulsterones 20mg
  • Yohimbine 3mg
  • Caffeine 200mg

Even the amounts contained are the same.

Synephrine is derived from the fruit of citrus aurantium, which is also known as bitter orange. It has long been used in Chinese medicine to treat chest congestion. It acts as a stimulant, and has some similar effects as ephedrine.This has been a large reason why synephrine has become a very popular alternative to ephedrine, and is widely used in various fat burners. Synephrine can help increase energy expenditure, increase metabolism, and also help suppress appetite. However, the effectiveness of this is still up to debate. Some studies have found it to be effective for weight loss while other studies do not support these types of claims. One study by Preuss et al. had stated that citrus aurantium appears to be a thermogenic substitute of ephedrine, but it still needs more studies to further confirm this. [1] You can read about synephrine in detail here.

Guggulsterones is derived from guggul plants, and has been extensively used in traditional Asian and Indian medicines. There are numerous health benefits of this such as lowering cholesterol levels, having anti-oxidant properties, cancer fighting abilities, and also weight loss benefits. Some studies have found guggulsterones have anti-obesity benefits where it helps reduce fat accumulation and also increase the breakdown of fats. We have a detail article about guggulsterones here.

Caffeine as we all know, is a mild stimulant with weight loss benefits. One cup of coffee has around 100 to 150mg of caffeine, so the 200mg contained in L6 and L6X is equal to about 1.5 to 2 cups of coffee.

Yohimbine is the last of the common ingredients shared in Lipo 6X and Lipo 6. It comes from a tree in Africa. It has aphrodisiac properties where it has long been used to increase libido, treat impotence, and enhance sexual performance. Obviously that's not why it's included in the formula here. There are some studies done that have found Yohimbine to have weight loss benefits and helps to improve body composition. For example, one study done on 20 professional soccer players found that oral dose of 20mg per day for 21 days had significant effects on decreasing body fat percentage. The study found that yohimbe supplementation helped to greatly lower body fat mass, and no side effects were reported. [2] You can read more about Yohimbe here.

>> Click here for Lipo 6

Nutrex Lipo 6X Fat Burner Review

The above covers all the key ingredients in L6, and these ingredients are also contained in Lipo 6X as well. On top of that, the L6x fat burner contains several extra ingredients including acacia rigidula, PEA (Phenylethylamine), Tyramine, and Hordenine.

As mentioned earlier, synephrine comes from citrus aurantium, which actually contains a combination of 5 different amines with synephrine being one of them. The others are hordenine, tyramine, octopamine, and N-methyltyramine. These can stimulate beta-3 cell receptors that can help increase metabolic rates. Hordenine is a known stimulant that can increase heart rate and blood pressure. It can also stimulate the release of norepinephrine. Phenylethylamine (PEA) is also a trace amine with stimulant effects on the central nervous system. There are also some claims that PEA improves mood and has weight loss benefits. Chocolates also contain PEA. Acacia Rigidula is a small tree more commonly known as Blackbrush Acacia. It contains adrenergic (having effects similar to epinephrine) amines that stimulate beta receptors leading to faster metabolic rate, lower appetite, and increased breakdown of fats.

Nutrex Lipo 6 and Lipo 6x Side Effects

I certainly hope that I haven't bored you with all the information of the key active ingredients in these diet pills; however, I think it's important to understand how the active ingredients work, and to find specific scientific studies to backup (or refute) the claims made by the manufacturers. With the hundreds (if not thousands) of diet pill products on the market today, and the lackluster regulatory enforcement, it's important to do some digging of your own to truly find out if a particular diet pill is all marketing hype with no real substance, or if it's worth its weight in gold.

In the above review of Nutrex Lipo 6 & 6x, we've laid out some scientific studies that speaks well of the ingredients used pertaining to fat loss and body fat composition; however, if it were a perfect world, everything in life would workout exactly the way we plan it. Unfortunately, it is not so, and like everything else, because the uniqueness of each individual, and each situation involved, what seems like the perfect solution in studies may turn out to be a real disappointment.

While considering all the factors of Lipo 6x, we cannot base our review of this diet pill solely on the basis of scientific studies, but also, we rely on the numerous feedbacks, reviews, and testimonials from actual users - users like yourself.

The Nutrex Lipo 6 diet pill received an average user rating of 3.6 out of 5. While most users had positive experiences with L6, there are users who did not speak well of it, and this will always be the case for any type of product. Each individual is uniquely different, and will experience different effects of Lipo 6x. Some individuals will have great fat loss success with almost no side effects, and other individuals will experience little to no weight loss with many side effects. It's never a for sure thing, and you just won't know until you've tried it yourself to know how you react to it. You can read all the Lipo 6 user testimonials here.

As with all fat burners and diet pills, Nutrex L6 and L6X has its side effects. Some side effects of Lipo 6 include:

  • Increase in energy levels
  • Anxiety, shaking, and light headedness
  • Cramps, numbness, light headaches, feeling faint
  • Increased heart rate and a rapid heart beat
  • Increased sweating
  • Nausea and upset stomachs
  • can disrupt sleep patterns, especially if taken late at night

Like all fat burners, do not start off with the full recommended dose. Instead, take only half dose for the first few days, get a feel for the diet pill, see how your body reacts to it, and if all goes will, then you can follow the suggested dosage.

>> Click here for Lipo 6



1. Preuss HG, DiFerdinando D, Bagchi M, Bagchi D.
Department of Physiology, Medicine and Pathology, Georgetown University Medical Center, Washington, DC 20057, USA.

2. Yohimbine: the effects on body composition and exercise performance in soccer players.Ostojic SM. Institute of Sports Medicine, Sports Academy, Belgrade, Serbia and Montenegro.