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Branched Chain Amino Acids
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Chrysin Supplement Information
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Everlast N.O. NitroPlex Review
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L-Glutamine information
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How Good is the Everlast N.O. NitroPlex Supplement?

Here's another review of the Everlast line of supplements for which I received free samples. A little while back I was contacted by a marketing rep for Everlast supplements, and was offered samples for their line of sports supplements, and I agreed to post reviews on these on our site. You can read our reviews of EverLast HyperPlex Protein Blend and HyperPlex Protein Bar here.

Disclosure: For the reviews done on the Everlast supplements, no payment or other forms of compensation were received. I received one tub of N.O. NitroPlex 1.93lb fruit punch flavor.

Everlast Sports Nutrition developed their Proline of supplements which includes NO NitroPlex, NitroPlex-6, HyperPlex protein bars, Hyperplex protein powder, and also Thermo Triplex for weight loss. Both NO NitroPlex and NitroPlex-6 are pre-workout supplements that's developed to help enhance strength, power, and endurance during workouts, while HyperPlex Protein Powder and Bars are developed to be sources of high quality protein. N.O. NitroPlex claims to be the:

"Ultimate Pre-Workout supplement formulated to support and enhance maximum vascularity, strength, power and endurance. N.O. NitroPlex gives you the energy to power through the most brutal workouts and provides the support nutrients your body needs for maximum recovery."

N.O. NitroPlex Benefits and Ingredients

N.O. NitroPlex contains various ingredients, designed to help enhance strength, power, and endurance. Below are some of the claimed benefits of N.O. NitroPlex:

  • Improved energy , motivation and Nitric Oxide (N.O.) levels
  • Heightened muscle Carnosine levels
  • Hydrogen ion (H+) buffering
  • Muscular Anerobic capacity
  • Improved resistance to muscular fatigue
  • Supports the transport and absorption of Creatine
  • Increased intensity
  • Focus, Clarity and Alertness
  • Vascularity, Pumps and Muscle fullness
  • Strength, power and endurance
  • Improved circulation and oxygen delivery
  • Improved adrenal function

N.O. NitroPlex Supplement Facts: 

Serving Size: 1 scoop(s) 
Servings Per Container: 38 

Amount Per Serving: 
Calories 55 
Total Fat 0 g 
Cholesterol 0 mg 
Total Carbohydrate 14 g 
Sugars 1 g 
Thiamin (as Thiamin Mononitrate) 0.5 mg 
Riboflavin 0.56 mg 
Niacin (as Niacinamide) 6.6 mg 
Vitamin B6 (as Pyridoxine Hydrochloride) 0.66 mg 
Folic Acid 133 mcg 
Vitamin B12 (as Cyanocobalamin) 2 mcg 
Biotin 100 mcg 
Pantothenic Acid (as d-Calcium Pantothenate) 3.33 mg 
Phosphorus (as Magnesium, Monopotassium & Monosodium Phosphate) 60 mg 
Magnesium (as Magnesium Oxide & Phosphate) 110 mg 
Sodium (as Monosodium Phosphate & Sodium Citrate) 320 mg 
Potassium (as Potassium Citrate & Monopotassium Phosphate) 50 mg 

Proprietary Blends: 23,000 mg 

Advanced Volume Performance Matrix: 
Glucose Polymer Blend 
Creatine Monohydrate 
Creatine Malate 
Creatine Citrate 
Creatine Pyruvate 

Accelerated Nutrient Delivery System - NO2 Releaser: 
L-Arginine alpha-Ketoglutarate (A-AKG) 
L-Arginine Ketoisocaproate (A-KIC) 
Prickly Ash Bark Extract 

Advanced Tissue Support & Repair: 

Advanced Energy Support & Insulin Support Factors: 
Calcium Pyruvate 
DGL (Glucuronolactone) 
Yerba Mate Extract 

Adaptogen & Fatigue Resistance Blend: 
L-Citrulline Malate 
Beta-Alanine (CarnoSyn) 
DMG (N,N-Dimethylglycine) 
Cordyceps Sinensis 
Eleutherococcus senticosus Extract 
Rhodiola Rosea Root Extract 

Focus, Clarity & Concentration Blend: 
DMAE (as DMAE Bitartrate) 
Ginkgo Biloba Extract 

RZ - RapidZorb Complex: 
Zingiber officinale Extract 

Other Ingredients: Maltodextrin, Citric Acid, Natural & Artificial Flavors, Malic Acid, Calcium Silicate, Lecithin, Xanthan Gum, Acesulfame Potassium, Sucralose, FD&C Red #40, FD&C Blue #2. 

EverLast N.O. NitroPlex Reviews

Ok, that's a rather long list of ingredients. Below, we'll quickly discuss what some of these ingredients are, and what they do.As you can see from the ingredient list, NitroPlex consists of 23,000mg (23g) of proprietary blend, which is made up of a several different blends such as:

  • Advanced Volume Performance Matrix
  • Accelerated Nutrient Delivery System - NO2 Releaser
  • Advanced Tissue Support & Repair
  • Advanced Energy Support & Insulin Support Factors
  • Adaptogen & Fatigue Resistance Blend
  • Focus, Clarity & Concentration Blend

Each of these blends contain several ingredients, so let's quickly go through some of the key ingredients here. The performance matrix consists of mostly creatine, such as creatine monohydrate, creatine malate, creatine citrate, and creatine pyruvate. At this point, I think we all know what creatine is, and what it does, so no need to get into much discussion here. You can read more about creatine in the following guide: Guide to Creatine Supplements

AAKG is a substrate for production of Nitric Oxide, which is what gives the "pumped" feel". Other benefits of AAKG includes improving muscle endurance and increasing peak power performance. AAKG has been extensively studied involving human subjects with good results. In a Canadian (University of Saskatchewan) study done on creatine, AAKG, and amino acids effects on endurance and performance, 35 male subjects with average age of 23 years participated. They were randomized to either a supplement group, or a placebo group. Body composition, muscle endurance (bench press), and peak / average power output were measured before and after supplementation. They found that with the supplement mix, bench press reps increased significantly compared to placebo group. Peak power also significantly increased for the creatine / AAKG group compared to placebo. [1]

Glutamine makes up over 60% of the amino acids in skeletal muscle, and during intense training, glutamine levels are greatly reduced, which effects your strength, stamina, and also rate of recovery. You can read more about glutamine here. Leucine is another important amino acid here, and it is a common amino acid found in proteins. Bodybuilders and other athletes use protein powders that contain leucine to promote muscle recovery. Leucine helps with regulation of blood sugar levels, and the growth and repair of muscle tissue. It helps to prevent the breakdown of muscle proteins that can occur after trauma or severe stress.

DGL (Glucuronolactone) is an ingredient that you will often find in energy drinks. Studies done on Glucuronolactone has found it to help enhance endurance and exercise performance.

Yerba Mate contains stimulants such as caffeine and theobromine. Yerba Mate has similar effects with other caffeinated drinks such as coffee and guarana beverages. It is known to help enhance the focus and alertness of the user, and is also a stimulant with negative side effects such as anxiety and jitteriness. We have a long and detailed guide on Yerba Mate here.

Two very exceptional ingredients of the Adaptogen & Fatigue Resistance Blend are L-Citrulline Malate and Beta-Alanine. The exceptional benefits of these two ingredient deserves a full write-up, and hence cannot be completely explained here. However, I will say here, that the combination of Beta Alanine and Citrulline malate is what I constantly use for my own homemade supplement stacks. In fact, you can read about my homemade supplement stack here:

Homemade bodybuilding supplements - 1
Homemade bodybuilding supplements - 2 (contains detailed information on beta alanine and citrulline malate)
Homemade bodybuilding supplements - 3

I'll give a very brief explanation of what these two ingredients are here, but if you would like to learn the details, see part 2 of my homemade bodybuilding supplements guide above. Beta alanine is a very interesting ingredient. It is a beta amino acid that boosts carnosine levels that works to delay the onset of muscle fatigue - in effect, allowing you to train longer, and train harder. Citrulline malate is a non-essential amino acid, and is not abundant in our diet, but it plays a role in regulating Nitric Oxide (NO). Citrulline Malate helps raise arginine levels more effectively, reduces the sensation of fatigue, increase ATP production during exercise by 34%, and increase phosphocreatine recovery after exercise by 20%. [2]

My NO NitroPlex Review and N.O. NitroPlex Side Effects

Anyway, looking at the ingredient makeup of Everlast N.O. NitroPlex, it looks like it contains a host of very good ingredients designed to boost endurance, energy, strength, and workout intensity. So how did I make out with the NO NitroPlex? For my workouts, I followed the bottle instructions and took 2 scoops with water about 30 minutes before my workouts, and just one scoop on non-workout days.. Please note, I took just one scoop for the first 3 days just to test my tolerance, since it does contain stimulants.

First of all, the taste. I got the fruit punch flavor. For me, the taste was about average. It's a bit hard for me to describe the taste, although I've had better tasting fruit punch flavors. Overall, I'd give it a 7 out of 10 for taste.

During my first few servings where I took just one scoop to test my tolerance, I can't say I felt any negative side effects, but I did notice a boost in my workout intensity. However, on training days when I took two scoops, I have to say that I noticed some strong effects - good and bad. Within about 10 to 15 minutes after consuming the drink (@ 2 scoops), I would start to feel a little jittery, and anxious. I start to feel like I have a lot of energy, and I became very anxious to get to the gym and burn off some of this excess energy. I also had noticeably increase heart rate, increased sweating, and heavier breathing - this was before I even hit the gym.

In the gym, the increase heart rate, sweating, energy boost all continued. I blasted through my workouts rather quickly - resulting from less resting in between sets. I had a huge boost in energy, strength, and endurance during my workouts. Overall, while I was taking NO NitroPlex, I had a great increase in my workout intensity. However, the downside of taking two scoops - for me, at least - was the negative side effects I experienced, which mainly was the increase in heart rate. Everything else was fine, but the increase in heart rate felt a little uncomfortable. I've used a lot of similar supplements, but no other made my heart race like NO NitroPlex did.

With that said, after several workouts at two scoops, I dialed it down to 1.5 scoops, and while I still had an increase in heart rate, it was not bothersome in any way. If you do use N.O. NitroPlex, my suggestion is to first test your tolerance with just one scoop for a few workouts, and if you're okay, then you can increase it to 2 scoops. The bottle instructions actually suggests taking 2 to 3 scoops per serving; however, unless your a big fella, and have very good tolerance, I'd suggest sticking with just 2 scoops.



1. Int J Sport Nutr Exerc Metab. 2008 Oct;18(5):493-508.
Creatine, arginine alpha-ketoglutarate, amino acids, and medium-chain triglycerides and endurance and performance.
Little JP, Forbes SC, Candow DG, Cornish SM, Chilibeck PD.

2. Br J Sports Med. 2002 Aug;36(4):282-9.
Citrulline/malate promotes aerobic energy production in human exercising muscle.
Bendahan D, Mattei JP, Ghattas B, Confort-Gouny S, Le Guern ME, Cozzone PJ.


Jan 2011