What is Nitric Oxide, and What are the Benefits of NO2 Supplements?
NO 2 Hemodilator is a highly hyped, and
"crazed" supplement on the market. Like when creatine
monohydrate first hit the market, NO2 is making a big splash
in the supplements industry and has many bodybuilders' interests
piqued, and just like when creatine first came out, it's
If you've seen some ads for NO 2 supplement, you'll see
the grand promises it makes:
- Huge gains in lean mass
- Accelerate fast twitch muscle
- Perpetual pumps
- Faster recovery and increased strength gains
So really, can the average Joe make fantastic gains with
this 'miracle' supplement?
NO 2 hemodilator was introduced by Ed Byrd, who also happened
to introduce creatine to the bodybuilding world. Given this
fact, it would seem NO2 has some potential.
NO 2 - nitric oxide background
Nitric Oxide was originally discovered in the 80's - come
to think of it, that's only about 20 years ago. Two scientists
were studying a mysterious gas that was only present for
an instant every time a muscle contracted and blood vessel
dilated. They eventually discovered this gas, and it was
called nitric oxide.
Hemodilation means widening of the blood channels, leading
to increased blood flow resulting in more nutrient and oxygen
How Does NO 2 Hemodilator Work?
As said above, nitric oxide is present only briefly when
a muscle contracts and blood vessel dilates. What it does
is increases blood flow. When you exercise, nitric oxide
is released causing blood surges, which is what you experience
- called the 'pump'. However, this is only temporary, which
is why you lose that awesome pumped feeling shortly after
you finish your workout.
What Ed Byrd has managed to do, is developed a NO 2 extended
release delivery system in what they call "pHyser3",
and this forces a continuous daily production of nitric
oxide, and you get a "perpetual pump".
Quote from NO 2 supplement ad: [Hemodilation
is initiated by nitric oxide synthesis. Nitric oxide is
the "cell-signaling" molecule responsible for blood flow,
oxygen delivery, glucose uptake, muscle velocity, power
output, and gene-expression, or muscle growth. By sustaining
nitric oxide levels in the skeletal muscles, NO 2 generates
its sustained hemodilation. The channels that deliver muscle
building agents to the muscle cells become "forced open"
and remain that way throughout the day. The results are
faster gains in lean mass, greater strength, increased endurance,
complete full-body muscle recovery, and a "perpetual pump."]
NO 2 Nitric Oxide and Creatine Information
Both creatine and NO 2 supplements are introduced by the
same person, Ed Byrd. So what's the connection between them
other than the originator? Creatine volumizes cells by pulling
water into the cell, which is known as water retention.
NO 2, by hemodilation, fills up the spaces between the cells
with blood, giving a continuous pump. The NO 2 is supposed
to make the creatine pump harder as well. This leads to
a synergistic effect between the two, and leading to greater
pumps and a very dense and hard look.
Aside from all this, the makers claim that the biggest
benefit of NO 2 Hemodilator is its ability to generate new
muscle growth, increase strength, and improve muscle recovery.
NO2 Supplement - The Low Down
All of the stuff they claim about NO 2 sure sounds enticing
huh? I have to admit, after looking into this supplement
(Nutraceutical Expressor as they call it), I am inclined
to shell out a little cash to try it. After all, the perpetual
pumps, increase in strength, better muscle growth and recovery,
and synergies with creatine makes it sound like one helluva
However, I looked high an low, and I have to tell you,
I cannot find one study conducted on effects of NO 2 that
backs up the claims made. That's right, those are just claims.
And without studies to substantiate the claims, one can
only go out on a limb and spend a hefty $80 bucks to buy
it, and hope for the best.
With that said, perhaps I can shed some light on the effectiveness
of NO 2 supplements based on real life experience feedback and reviews I have received from users.
From the small sample of user feedbacks I've received,
I have tabulated their results with NO 2 Hemodilator as
- Positive response - 9
- Neutral response - 3
- Negative response 5
- 2 Users experienced a 2 to 3lb gain in weight
- 1 user reported going from 205 to 226lb (21 lbs) in
- 1 user reported going from 225 to 242lb (17 lbs) in
- 13 users experienced no noticeable weight gain
- 1 user experienced headaches and migraines
- In general, there's an increase in overall strength
- All positive feedbacks reported noticeable pump, and
a prolonged pump, with fuller and harder muscles
Update: 2 very popular BSN NO2 products have recieved close to 1,000 user reviews in total on our site, one is BSN Nitrix, and the other is BSN NO Xplode. The average rating from all the user reviews we received is 4.0/5.0. I can't possibly go through all these reviews and re-tabulate the results, but you can read the many user reviews we've received here.
These are the highlights from the reviews I received. Obviously,
weight gain is not as apparent as the claims make it out
to be, with only 2 users reporting extraordinary gains,
and 2 users making gains in the 2 to 3lb range, and the
rest with no noticeable weight gain. Other than that, NO
2 hemodilator does live up to its claims for generating
Obviously, this is in no way a scientific measure of NO
2, but at least it does give some objective review of actual
user feedback and experience with NO 2.
NO 2 Side Effects
While there isn't much documented side effects of using
NO 2 supplement, high doses of arginine maybe toxic, and
over use can lead to diarrhea and nausea. As said above,
one user did experience headaches and migraines. Other than
that, there isn't much more to say about its side effects.
There are other Nitrc Oxide products available now, with
exactly same ingredients consisting of 3000mg of arginine
Alpha-ketoglutarate. For example, popular alternatives include
Pinnacle's popular NOx2, BSN Nitrix, or Universal NOx3.
(All have the same ingredients.) The main difference is
Click here for MRI NO2 Black
Click here for BSN Nitrix