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Back Pain Treatment
Back Pain Relief - Lower Back Pain
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Calcium Deficiency
Cause of Lower Back Pain
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Degenerative Disc Disease
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Joint Pain & Joint Health - 1
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Lactobacillus Acidophilus
Lifezyme Plus - Pain Relief
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Vitamin Guides & Articles

Vitamin for Acne Treatment
Vitamin A & Beta Carotene
Vitamin A Deficiency & Carotene
Vitamin B Complex Benefit
Vitamin B1 Thimaine
Vitamin B1 Thiamine Deficiency
Vitamin B2 Riboflavin
Vitamin B2 Riboflavin Deficiency
Vitamin B3 Niacin
Vitamin B3 Niacin Deficiency
Vitamin B5 Pantothenic Acid & Acne
Vitamin B5 Pantothenic Acid Benefit
Vitamin B6 Pyridoxine
Vitamin B6 Pyridoxine Health Benefit
Vitamin B7 Biotin & Hair Loss
Vitamin B7 Biotin Deficiency
Vitamin B9 Folic Acid Pregnancy
Vitamin B9 Folic Acid Deficiency
Vitamin B12 Benefit & Side Effects
Vitamin B12 Deficiency & Symptoms
Vitamin C Ascorbic Acid
Vitamin C Health Benefits
Vitamin C Deficiency Symptoms
Vitamin C and Vitamine E
Vitamin D Benefits
VItamin D Deficiency Symptoms
Vitamin E Health Benefit
Vitamin E Deficiency Symptoms
Vitamin K Food & Benefit
Vitamin K Deficiency Symptoms
Vitamin K Supplements

Vitamin B2 Riboflavin Deficiency & Benefits

Vitamin B2 Riboflavin and Your Eyes

Age-related cataracts are the leading cause of visual disability in the U.S. and other developed countries. Research has focused on the role of nutritional antioxidants because of evidence that oxidative damage of lens proteins from light may lead to the development of age-related cataracts.

Two case-control studies found significantly decreased risk of age-related cataract (33% to 51%) in men and women in the highest quintile of dietary riboflavin intakes (1.6 to 2.2 mg/day) compared with those in the lowest quintile (0.08 mg/day). Individuals in the highest quintile of riboflavin nutritional status, as measured by red blood cell glutathione reductase activity, had approximately one half the occurrence of age-related cataract as those in the lowest quintile of riboflavin status, though the results were not statistically significant.

A cross-sectional study of 2,900 Australian men and women, 49 years of age and older, found that those in the highest quintile of intake for riboflavin were 50% less likely to have cataracts than those in the lowest quintile. Another study of more than 50,000 women did not observe a difference between rates of cataract extraction between women in the highest quintile of riboflavin intake (1.5 mg/day) and those in the lowest quintile (1.2 mg/day). However, the range between the highest and lowest quintiles was small, and median intake levels for both were above the current RDA for riboflavin. Although these observational studies provide support for the role of riboflavin in the prevention of cataracts, placebo-controlled intervention trials are needed to confirm the relationship.

B2 Riboflavin Preventing Migraines

Some evidence indicates that impaired mitochondria oxygen metabolism in the brain may play a role in the pathology of migraine headaches. As the precursor of the two flavin coenzymes (FAD and FMN) required by the flavoproteins of the mitochondrial electron transport chain, supplemental riboflavin has been investigated as a treatment for migraine.

A randomized placebo-controlled trial examined the effect of 400 mg of riboflavin/day for 3 months on migraine prevention in 54 men and women with a history of recurrent migraine headaches . Riboflavin group was significantly better than placebo in reducing attack frequency and the number of headache days, though the beneficial effect was most pronounced during the third month of treatment.

It should be noted, however, that only about 25 mg of riboflavin can be absorbed in a single oral dose. A more recent study by the same investigators found that treatment with either a medication called a beta-blocker or high-dose riboflavin resulted in clinical improvement, but each therapy appeared to act on a distinct pathological mechanism; beta-blockers on abnormal cortical information processing and riboflavin on decreased brain mitochondrial energy reserve. Though these findings are preliminary, they suggest that riboflavin supplementation might be a useful adjunct to pharmacological therapy with beta-blockers in migraine prevention.

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Vitamin B2 Riboflavin Deficiency

Certain groups of people are at a greater risk being deficient in riboflavin. They are individuals with kidney disease who are being treated with dialysis; individuals with absorption problems; women who are pregnant with more than one fetus; and women who are breastfeeding more than one infant. In addition, chronic diseases such as cancer, heart disease, and diabetes mellitus are known to trigger vitamin B-2 deficiency.

Sources of Vitamin B2 Riboflavin - Normally, people may get required riboflavin from the following food sources: Beef Liver, Dairy Products, Eggs, Meat, Wheat Germ and Tuna.

However, the following people are usually deficient in riboflavin and may need extra Vitamin B2 from supplements:

  • Women who are pregnant or breastfeeding
  • Anyone with inadequate caloric or nutritional dietary intake or increased nutritional requirements (ie. when you work out regularly)
  • Athletes
  • Those who drink alcohol in excess
  • Those under long term excess stress.
  • People who just had undergone surgery
  • People who have hyperthyroidism

Vitamin B2 Riboflavin Deficient Symptoms

True riboflavin deficiency is quite rare. When riboflavin deficiency symptoms do occur, they're usually related to a shortage of all the vitamin B's. Usually, though, riboflavin deficiency shows up as problems with the mucous membranes, skin, eyes, and blood. An early and clear sign is sores and cracks on the corner of the mouth. Scaly skin, reddened eyes, and anemia are other deficiency signs.

When you have any of the following symptoms, please consider take some extra Vitamin B2 supplement pills to enrich your riboflavin level:

  • Sore lips
  • Inflammation of tongue and lips
  • Eyes overly sensitive to light and easily tired
  • Itching and scaling of skin around nose, mouth, scrotum, forehead, ears, scalp
  • Trembling
  • Insomnia


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