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Originally Posted by fitme
does it wipe you out totally though? I think i really need something so i'm not soo hyper..if i'm not so hyper i would be able to sleep right?..like right now i'm sooo hyper i really should be sleeping...lol
any sides?
i just want to be able to fall asleep naturally? make sense?
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This is from the National Institutes of Health:
Melatonin is a neurohormone produced in the brain by the pineal gland, from the amino acid tryptophan. The synthesis and release of melatonin are stimulated by darkness and suppressed by light, suggesting the involvement of melatonin in circadian rhythm and regulation of diverse body functions. Levels of melatonin in the blood are highest prior to bedtime.
Sleep enhancement in healthy people:
Multiple human studies have measured the effects of melatonin supplements on sleep in healthy individuals (59;60;61;62;63;64;65;64;62;63;66;67;68;69;70;71;6 0;61;72;73;74). A wide range of doses has been used, including "low-dose" melatonin (0.1 to 1.0 milligrams), or doses between 5 and 10 milligrams, often taken by mouth 30 to 60 minutes prior to sleep time. Most trials have been small, brief in duration (often single-dose studies), and have not been rigorously designed or reported (inadequate blinding and randomization). However, the weight of scientific evidence does suggest that melatonin decreases the time it takes to fall asleep ("sleep latency"), increases the feeling of "sleepiness," and may increase the duration of sleep. Better quality research is needed in this area. It is not known how melatonin compares to standard therapies used for insomnia, such as benzodiazepines like diazepam (ValiumŽ) and lorazepam (AtivanŽ), or other sleep aids such as zolpidem (AmbienŽ).
Depression (sleep disturbances):
Depression can be associated with neuroendocrine and sleep abnormalities, such as reduced time before dream sleep (REM latency). Melatonin has been suggested for the improvement of sleep patterns in patients with depression, although research is limited in this area (168;169;170;171). Further studies are needed before a clear conclusion can be reached.
Side Effects and Warnings:
General: Based on available studies and clinical use, melatonin is generally regarded as safe in recommended doses for short-term use. Available trials report that overall adverse effects are not significantly more common with melatonin than placebo (20;21;18). However, case reports raise concerns about risks of blood clotting abnormalities (particularly in patients taking warfarin), increased risk of seizure, and disorientation with overdose.
I hope this helps.