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This is a FAQ to answer most typical questions. Please read EVERYTHING in here as it has TONS of knowledge on PH use, post-cycle, and everything in between.
Courtesy of Pogue - Prohormone FAQ By pogue pogue22@ziplip.com Revision 1.3 - 6/12/03 Special thanks to Tkarrde & roobear Included here are some of the most common questions asked about prohormones. This has been compiled into information based on some scientific studies, but mostly from user feedback after years of success using prohormones. Please keep in mind that this document might have some errors and you will need to do much more reading before you decide whether or not use prohormones. 1. What are prohormones? Prohormones are synthetically manufactured compounds which convert to anabolic hormones via enzymes in the liver; hormone precursors. They are commonly abbreviated as PHs. 2. What are they used for? Prohormones are used by athletes looking to increase size, strength, endurance, reduce recovery time or add lean body mass. They are most often used for increasing muscle mass or reducing bodyfat levels. Life extension groups are also increasingly using prohormones as a means of hormone replacement therapy, as an alternative to prescription drug use. 3. Do they have side effects? Yes. Prohormones can have the same side effects as anabolic steroids, and are dependant upon the user as to which side effects one might experience. Some side effects are acne, hair loss, breast tissue enlargement, and prostate swelling. The potential for these side effects does exist, but it can be reduced if one uses proper precautionary measures (see below). Generally, if a person is genetically predisposed to a side effect it will occur (i.e.: if someone has a history of male pattern baldness in the family, it could be assumed that this could be a side effect experienced if certain prohormones are used) 4. Which prohormones convert to which compounds? Here is a list 4 androstenediol (4AD or 4diol) converts to testosterone 19 nor-4-androstenediol (Nordiol or nordiol) converts to nortestosterone or nandrolone 1 androstenediol (1AD) converts to 1-testosterone (dihydroboldenone) 1,4 androstenedione and 1,4 androstenediol (1,4andro or Boldione) converts to boldenone and slightly converts to estrogen (the diol version does not convert to estrogen) 5 alpha androstenediol (5AA) converts to DHT 3 beta androstenediol (3 beta) converts to DHT 3 alpha androstenediol (3 alpha) converts to DHT 4 hydroxy androstenedione converts to 4 hydroxy testosterone which is an aromatize inhibitor (blocks formation of estrogen) 7-KETO-DHEA does not convert to any active anabolic compounds 1-testosterone (1-test) is already an active compound and does not need to undergo conversion Compounds you want to avoid. 5 androstenediol (5AD or 5diol) converts to testosterone at a very low rate and is an estrogen agonist 4 androstenedione (andro) converts to testosterone and estrone (estrogen) 19 nor-4-androstenedione (norandro) converts to nortestosterone and estrogen DHEA converts to androstenedione and can be converted to all other hormones Pregnenolone converts to progesterone and can be converted to all other hormones 5. How do prohormones work? Basically, when they are administered into the system, they are broken down in the liver and converted to their target hormone via certain enzymes. There have been a number of quotes describing how much of the hormone is converted, but there is no definitive answer as to how much of the prohormone is converted into its target active. Once a certain amount is created, the enzymes used for conversion become saturated and no more can be converted. This is true with all the compounds, except for 1-testosterone which really isn't a prohormone. 6. What do the target hormones do? Each hormone works in different ways once it is converted, but essentially it attaches to an androgen receptor in the cells of your body. This in turn increases nitrogen retention and protein synthesis, meaning that your body is in a constant anabolic state (assuming you are continuously supplying your body with the hormone). Here is a brief description of each hormone and what it does. Testosterone is the primary male hormone responsible for development of the sex organs and muscle growth. Testosterone is both anabolic and androgenic-anabolic meaning it causes muscle growth and androgenic meaning that it causes development of secondary sex characteristics. Testosterone converts to both DHT and estrogen in its parent form. Testosterone is often the primary hormone used on a cycle of steroids. It is a mass builder, and will often help with unwanted androgenic side effects of other steroids. Although conversion to estrogen can cause many unwanted side effects on its own, testosterone should generally be the base to any cycle. Nandrolone is an anabolic hormone, with not as much androgenic potential. It attaches to the androgen receptor with greater affinity than testosterone, but can cause a loss of libido and generally stays active in the system much longer than does testosterone. This is the "safest" choice for users who want to avoid most common side effects. DHT (dihydrotestosterone) is the primary androgenic hormone in the body. It is responsible for increases in strength, as well as most of the unwanted side effects common with steroids. DHT is converted from testosterone via the 5 alpha reductase enzyme. DHT receptors are high in the scale, skin and prostate; high DTH levels are the most common cause of prostate swelling, acne, and male pattern baldness. Boldenone is a veterinary hormone, which is commercially sold as Equipoise. Equipoise is known as an alternative to nandrolone when using steroids. It provides an increase in appetite, with some fat burning potential. Boldenone converts to estrogen at about half the rate of testosterone. Those who are looking to avoid some of the stronger androgenic side effects also commonly use it. 1-testosterone is the 5 alpha reduced version of Boldenone. 7. How do I take prohormones? There are three common routes of administration for prohormones. These are usually based on their efficacy (i.e. how much is absorbed). Since the liver and stomach lining breaks down prohormones rather efficiently, taking them orally is the poorest route of administration. Most users prefer transdermal (topical) administration. When taken this way, you apply it to your skin and it will continue being absorbed over a period of 12 hours or so. Cyclodextrins or sublingual methods are also commonly used, which is where the prohormones are dissolved under the tongue. This also has a high level of absorption and works well. There are also some products on the market which are sold as "intraoral" or "intranasal". These are meant to be sprayed into the nostril prior to your workout, and are generally only meant as preworkout boosts, not for a cycle of prohormones. Some manufactures have started selling prohormones in oral form with an ester attached. This, in theory, will allow it to be slowly absorbed for many hours similar to the other methods, but to my knowledge, there have been no studies demonstrating that this method increases bioavailability. 8. What is a cycle? What does stacking mean? A cycle is generally used to describe a length of time and common dosage when taking prohormones. Stacking means taking more than one prohormone at a time to increase gains or reduce side effects. Common cycle lengths are 2 weeks, 4 weeks, 6 weeks, and 8 weeks. I recommend 4 week cycles, which seem to give the most gains with fewer sides. I would not recommend going beyond 8 weeks. Common stacks are 4AD and Nordiol, 1AD and 4AD, 1-test and 4AD, etc. You will notice most everything is stacked with 4AD. This is because testosterone gives you a bit more leverage, providing good gains and overall anabolism, with reduced androgenic side effects. Each of the prohormones can be taken alone, or taken together. The choice is yours and should be made from reading this text, and all the user feedback from this board and others. Research, research, research! 9. What is post cycle therapy? Post cycle therapy is a tried and true method of helping to solidify your gains by raising natural testosterone levels and lowering estrogen levels once your cycle is over. When you add external hormones to your body, your own natural production becomes suppressed. Your body attempts to compensate your endocrine system by stabilizing the other hormones, which results in an increase in estrogen. Once you quit supplying your body with external hormones, your natural testosterone will be low and estrogen will be high. Therefore, anti-estrogens are taken to halt the manufacture of estrogen in the body. This will result in higher testosterone levels, hence making it easier to keep your gains. Post cycle therapy should begin the next day after the prohormones have stopped being taken. Common post cycle therapy drugs are listed below with dosages: 6OXO 6oxo is an aromatize inhibitor sold by Ergopharm. It is the best over the counter anti-estrogen available for post cycle use. Week 1 - 600mg daily in two divided doses, morning and night Week 2-3 - 400mg daily Week 4 - 300mg daily Formasin/Formastat/Aromazap Note: 4 hydroxy androstenedione acts as a weak androgen and can cause further suppression of natural testosterone, but can be used post cycle. Dosages should be 250mg a day for the first two weeks, followed by anywhere from 50-250mg a day for the next two. Clomid Clomid is a prescription fertility drug, but is highly available and highly effective at blocking estrogen and increasing LH output. Day 1 - 300mg Day 2-11 100mg Day 11-21 50mg OR 150mg daily for 2 weeks 100mg daily for 2 weeks Nolvadex Nolvadex is also a prescription, which is highly available and blocks estrogen at the receptor. Week 1-2 - 40mg daily Week 2-4 - 20mg daily There are other prescription anti-estrogens available, but these two will be fine unless side effects arise, so we won't discuss the other options in this FAQ. Other common post cycle favorites including high doses of flax oil, ZMA, tribulus and an ECA stack coupled with reduced training volume and increased calories (500 or so above maintenance). But, it is very important to use an anti-estrogen for post cycle. I would never recommend not using one unless the cycle length is 2 weeks or less. 10. What dosages should I use? Dosages are different for the different routes of administration and for the different hormones taken. Here is a basic outline of each prohormone along with general cycles used, based on user feedback. For your first cycle, I recommend sticking to a lighter dosing schedule for 2-4 weeks. Note: This is a general guideline. Dosages for any cycle can be higher or lower, and some products may incorporate one or more of these compounds so that the below amount might not be able to be achieved. This is just a basic outline and is far from completely accurate. 1AD 1AD is by far the most popular prohormone. It is considered to be the most effective taken orally, and has resounding user feedback. It is best stacked with 4AD to reduce side effects, the most common of which include lethargy and reduced libido. 1AD should not be used transdermally, and could be used sublingually, although there are few products with this delivery system used. 1AD is commonly stacked with 4AD and shouldn't be stacked with nordiol, or the DHT precursors. 4-6 week cycles are best taken at anywhere from 300-900mg daily. Take in divided doses throughout the day to keep blood levels elevated. 4AD 4AD is the next best. It is almost always used with other hormones due also to its resounding user feedback and adding large amounts of mass from increases in testosterone and estrogen. 4AD can be taken orally, transdermally, or sublingually. 2-6 week cycles are generally used. 4AD can be stacked with just about anything. Oral: 300-1500mg daily. Oral is probably the worst way to take this, but if you are simply looking to reduce sides of 1AD, etc - it works. Take in divided doses to ensure elevated blood levels. Transdermal: 400-600mg daily with two applications in morning at night. Sublingual: Probably 15-50mg at a time, 3 times or more daily in divided doses. Nordiol Nordiol is the best prohormone for use by people who want to avoid the common androgenic sides associated with the other hormones. Can be taken orally, transdermally or sublingually. 2-4 week cycles recommended. Heavily suppressive, despite what literature says. Nordiol is commonly stacked with 4ad for mass, or 1,4andro for cutting or users wanting reduced sides effects. Oral: 500-800mg daily in divided doses Transdermal: 500-800mg daily in split doses morning and night Sublingual: 15-50mg in divided doses 1,4andro 1,4andro is renowned for causing appetite stimulation. It's low in estrogenic sides and good for cutting or bulking. Some people claim that transdermal administration works well, but the feedback I've seen has been poor. Oral seems to be the route of administration, and the dione version appears to work better than the diol. 1,4andro can be stacked with just about anything. Taking 1,4andro for less than 4 weeks is generally a waste because it takes quite a while for the effects to kick in. Oral: 300-600mg daily in divided doses. Transdermal: N/A Sublingual: N/A 1-testosterone 1-test is the active form of 1AD and is best taken transdermally or sublingually, although oral products suspended in oil with an ether attached also have very good feedback. 1-test is best stacked with 4AD for mass or 1,4andro for cutting. Oral: 150-300mg when taken in ethergel product in divided doses Transdermal: 200-500mg daily or more in split doses Sublingual: Not sure 5AA/3 beta/3 alpha These all convert to DHT at different rates and have slightly different properties. I'm a little hazy on all of them, except that 5 alpha can compete with estrogen for receptor activity when converted to DHT. Some people have used 5AA in an oral product as a preworkout boost, while others have used 3 alpha for a "hardening" agent. Thanks to roobear for the below info on DHT precursors Quote:
This is slightly out of the scope of this FAQ, but is generally used for cutting. This has been shown to increase thyroid output and lower cortisol levels, without converting to target hormones. Used for cutting stacked with other thermogenic compounds for 4-6 weeks. Oral: 200mg in two divided doses Transdermal: 100mg daily 11. Are prohormones legal? Yes, currently they are legal in the US and some other countries. Please visit www.usfa.biz and write your politicians to ensure they stay that way. Prohormones are not tested for in job drug tests, but they are probably banned and can potentially show up on a drug test for athletics. Check your local laws for specific information. 12. Who should use prohormones? Mature adults above the age of 21 looking for increases in lean muscle mass or decreases in bodyfat levels. Most veterans will advise using prohormones after several years of training, to ensure you have a good feel for proper diet, nutrition and supplementation. Using prohormones under the age of 18 is a very bad idea; it can result in the closure of growth plates, thus resulting in permanently stunted growth; it can also result in potentially serious endocrine system problems. Those with potential for or already enlarged prostate or those susceptible to male pattern baldness should not use prohormones; nor should prohormones be used by people with heart conditions, who currently have gynocomastia, or have liver or kidney problems. If you have any doubts, see a doctor before using these compounds. 13. Can I take prohormones along with steroids? This is a hotly debated subject. Yes, you can - but why? If you have access to steroids, why would you bother with prohormones? Anabolic steroids are already hormones in their current form and require no conversion - hence, they are more powerful, albeit illegal. The only compound I would say that you could take with any other steroid would be 1-testosterone, which would be an equivalent of Primobolan or Equipose. The only other thing I can think of would be taking 4AD with Fina to reduce side effects. There is more information about this on boards like Anabolicminds or Animal's board. 14. How can I avoid some of the potential side effects associated with prohormones? There are certain ancillary compounds available to treat potential side effects of prohormones. Below is a list I compiled which is pretty basic and should help clarify some of the issues of side effects. Prostate Issues The prostate is an organ at the neck of the bladder where it joins the urethra. It is responsible for controlling urination and ejaculation. Common symptoms of prostate problems are frequent or difficult urination, dribbling when urinating, erection difficulty, and pain in that general area. Either a rise in estrogen or DHT levels from increased testosterone, etc., probably causes this. If you have ongoing prostate issues, it's best not to use prohormones, though potentially the use of nordiol might be acceptable. Herbal treatments: Saw Palmetto Extract - Usual dosage is 160mg several times daily Beta sisterol or plant phytosterols - 300mg several times daily Flax seed oil - anywhere from 5-20 tblspoons daily Prescription Treatments: Proscar/Propecia - blocks the conversion of testosterone to DHT. Ineffective with DHT derived hormones (1-test, 1ad, 5aa, etc) Spironolactone - an anti androgen. Best not used for this, but used topically (more below) Acne Acne is very common on prohormone cycles, and can range from mild to moderate. It will go away once post cycle treatment concludes, or within a few weeks of cession of the product. The best way to treat acne is with the soaps available at your local grocery store or pharmacy. Just pick up some Neutrogena or whatever and scrub your face twice a day or use the body wash. Hair Loss Hair loss is caused by increased levels of DHT. Since DHT receptors are heavy on the top of the scalp, some people will notice a lot of shedding or a receding hairline on some cycles. There are various treatments for this; the most common is topical Spironolactone available from Nizoralman or Dr. Lee. The 2% will work as a preventative measure, while the 5% will attempt to help grow some hair back. There are also other methods, such as azelaic acid or Nizoral shampoo, but they are not proven to be effective as spiro is. If you are concerned you are losing your hair and are currently taking something to help prevent it, prohormones are probably not the best idea. If still interested in using prohormones, Nordiol might be the best option available to you. Gyno Gynocomastia, or development of the breast tissue, is sometimes common among aromatizing (converting to estrogen) prohormones. The first symptoms are puffy and itchy or swollen nipples. If you start to notice this while on a cycle, you need to start taking Nolvadex immediately. Formasin/Aromazap/Formastat might work, but 6oxo is not going to help this in most cases, so Nolvadex should ALWAYS be on hand for this situation. It is highly available, not very expensive, and not illegal to posses, so there is no reason not to have it. Don't wait and order some when you start to get the first signs of gyno, because Nolvadex needs to be taken as soon as symptoms of gyno appear. Start taking 40mg a day until the symptoms subside, and you may want to continue to take 10mg the rest of your cycle as precaution. Liver/Kidney Prohormones have to pass through your liver in order to convert, no matter what the route of administration, so higher levels of liver enzymes in the blood is common during a cycle. Many steroid users take Milk Thistle and ALA at high doses to combat this, and if you are concerned it would be a good idea to take one or both of these to help that. Problems with kidneys have not been an issue to my knowledge, but steroid users will often also take cranberry juice extract to help with that. Depression Some people report mild or moderate depression, especially post cycle when using 6oxo. This can be cured with prescription drugs such as Zoloft, Prozac, Paxil, etc. It can also be fought with herbal supplements such as St Johns Wort, 5-HTP or Sam-E. If you go with the herbal route, St Johns Wort should be 300mg 2-3 times daily, 5-HTP at 100mg several times daily, or 100-200mg of Sam-E once daily. You can combine all three if depression is extreme, otherwise my pick would be St. Johns Wort. Testicular Atrophy Many users report testicular shrinkage during a cycle. The testes will come back to full size once you start post cycle. If they do not, then it's recommended you take Clomid and possibly even HCG to help restore them. Sleeplessness Some people report having trouble falling asleep or staying asleep on a cycle. My recommendation is to take 1mg to 3mg of melatonin 30 minutes before bed time. Some other options are Valerian root, GABA, Tylenol PM or Kava Kava (potentially stressful on the liver). 15. What kind of training should I use when using prohormones? Everyone has their own opinion on this, and you should use whatever works for use. Most people put an emphasis on higher volume while using prohormones, and you can add more isolation sets and workout more frequently due to increased recovery time. But don't overtrain. Just because you're using prohormones doesn't mean you need to train daily or twice daily. Also, doing cardio on prohormones is fine. I recommend 2-3 times weekly of 20 minutes, if at all. 16. How should I eat when on prohormones? Try and eat 1-2g of protein per pound of body weight. Try and eat 500-1000 calories above maintenance, or more if bulking. Generally, standard nutrition guidelines should be followed. If cutting, try and eat 10-12 calories per pound of bodyweight, while keeping protein high. 17. Should I take any other supplements while using prohormones? Take whatever you normally take. If you take creatine, it's fine to continue taking it while using prohormones. Some people prefer to save it for post cycle to help retain some of the water weight. Otherwise, the usual stuff like a multivitamin, a good protein powder and flax seed oil should be standard issue for any athlete. 18. What are some good manufacturers of prohormone products? My personal picks would be Molecular Nutrition, Ergopharm, Avant Labs, BDC Nutrition, San, Syntrax or 1 fast 400. These are stand up companies that generally pump out quality products. 19. Can I make my own prohormone transdermal/oral/sublingual? Yes, there are several companies that offer prohormone powders in bulk such as Kilosports, Beyond a Century and 1 fast 400. You can buy powders from them and make your own capsules, cyclodextrins or transdermals easily. Visit Anabolicminds or Avant Labs message boards for a wealth of how-to information. 20. Can I inject prohormones? This is out of the scope of this FAQ, but yes you can. The results have been mixed, there have been some questions of products purity used in injectables, and there is a question of whether or not using them for this purpose is legal. 21. Is there anything I should know about transdermal delivery? Transdermals should be applied twelve hours apart. It is a good idea to apply them after showering and to rotate application spots daily. Apply lotion to application spots not in use. This is a good way to avoid a rash from the topical, which is a common side effect reported by users. Some prefer to scrub themselves with a luffa or sponge before applying them to remove the first layer of dead skin cells for optimal delivery. It is also a good idea to wear latex gloves when applying, and wash your hands when you are finished to avoid getting the solution into your eyes or other sensitive areas. Keep in mind that high amounts of sweating or getting the area wet too soon after application will wash it off, so it might have to be reapplied if this occurs. 22. Is there anything I should know about oral/liquid delivery? There are many products on the market with liquid delivery systems. You will need to drink these, and most of them taste badly. Just try and get them down as quickly as possible, or mix with another flavored liquid to help the taste. Also keep in mind that liquid and oral delivery methods are generally less effective. Even if the product is esterfied, it is still a good idea to take it several times daily in small divided doses to ensure saturated blood levels at all times. 23. Is there anything I should know about sublingual delivery? Try and let the product dissolve under your tongue and do not eat or drink anything for around 10-20 minutes after you take the product. As with orals, you will need to take it several times daily to maintain blood levels. 24. Which prohormones are best used in a bulking cycle and what kind of gains can I expect? Most people prefer the combination of 1-test and 4ad. This is a tried and true stack combination and most people seem to gain the best from it. Adding 1,4andro is also common to increase appetite and may help gains. How much one will gain off a cycle depends on your diet and training but gaining 10lbs in 4 weeks is quite common. 25. Which prohormones are best for a cutting cycle? Most commonly, people will use non-aromatizing hormones such as 1-test or DHT precursors to act as an anti-catabolic and increase hardness. However, low doses of 4ad may help, and adding 1,4andro can also be beneficial. 26. Is it okay to drink alcohol while taking prohormones? No, it is a really poor idea to drink while doing bodybuilding/weight lifting in general, but taking them while using prohormones is even worse. Taking large amounts of prohormones, especially orally, can cause increased liver stress. When you add alcohol into the equation it is a potential for disaster. If you have to drink, try to do it moderately and take milk thistle and/or ALA to help combat potential problems. Although, it would be best to avoid it completely. 27. Are there any other good documents I can read about prohormones or related topics? Yes, there are several, but they are slightly dated. Prohormones 4AD Information and conversion rates by Patrick Arnold Prohormone breakdown by Big Cat Post Cycle Therapy Understanding Post Cycle "T" Recovery by William Llewellyn Clomid, Nolvadex and Testosterone Stimulation by William Llewellyn Coming Off a Cycle by Marcus Haidam If you have any other good links, please let me know and I will add them. 28. Can I overdose on prohormones? Possibly, if you are taking over a gram to two grams a day orally then it could cause some liver strain or stomach discomfort - it will also probably increase the side effects of the hormone. You should never go over 2 grams daily for prohormones, you will not see anymore gains, the side effects will probably be unbearable and most likely the enzymes will be saturated for them to be effective. 29. I can't grow! Should I use prohormones? No. Anyone should be able to grow naturally without the use of prohormones; prohormones merely speed up the process. If you can't grow naturally, please post your diet, training and supplement routine for review. Most likely, you are making some errors-so please try and correct these basic issues before you resort to using prohormones. They are not magic and will not work without proper diet and training. 30. Can women use prohormones? Yes, they can - but the doses shouldn't be as high as using it for men. Using less androgenic hormones like Nordiol or 1,4andro is recommended above the others and no anti-estrogen is needed post cycle. I would recommend using nordiol at 300mg daily or 1,4andro 300mg daily for 2-4 weeks and tapering off the dosages slowly towards the end and possibly using tribulus extract post cycle. 31. When's the best time to take oral prohormones and should I take them with food? You want to take them in divided doses through the day, the standard is 3 doses 3 times daily. Taking them with food is optional, but if you take them with a high fat meal they can help absorption. Also keep hydrated (you should be doing this anyway) so as to avoid a burning sensation when urinating, as experienced with some prohormones. Most prefer to take them preworkout to give them a little extra boost. 32. Can I be drug tested for prohormones? Since prohormones convert into active anabolic compounds, it is the concern of some that they will be tested for in a drug test. The answer is almost always no, they will not show up in a drug test. Drug testing for anabolic steroids is very expensive and has to be asked for specifically. So, unless you are on probation for steroid use, or are a professional athlete, you will not be tested for prohormones/steroids. Also, since most prohormones have very short half lives, they will clear out of your system within a matter of days. General drug tests only test for opiates, ampetamines, cocaine and marijuana. However, if you are planning to join the military, or a sports organization that bans the use of these substances, it would be in your best interest to avoid them. ---------------------------------------------------------------------------------------------- Prohormones FAQ: Update By pogue pogue22@ziplip.com 12/26/03 The data contained in this update has been compiled mostly from user feedback along with some data present in compounds that have been released to the public in the past, or information from the pharmacutical companies that created these compounds. It is always a good idea to have a full physical before using these substances, along with having blood work done to check for liver/kidney anamolies. New Compounds Methyl 1-Test Methyl 1-Test is 1-testosterone with an alteration to the molecule that allows it to pass through the liver more freely without degredation. When a compound is methylated it changes the physical structure of the compound and it tends to act differently in the body. In the case of methyl 1-test, it seems to be a much stronger anabolic without particularly androgenic sides. Methyl 1-test is being sold in 5mg and 10mg tablets, as well as in powder and solutions. It seems to differ from other methylated compounds such as Winstrol and Dianabol in that it is more stronger mg per mg without very much conversion to DHT. The typical dosing pattern seems to be 5-10mg once daily. Those above 200lbs or experienced steroid/prohormone users might see benefits in 20mg ore more, however the side effects seem to be harsher the more you use. Some of the more common side effects reported are lethargy, decreased appetite, very painful pumps as well as high blood pressure. Methyl 1-test is a very powerful compound and is not recommended for beginners. This is clearly a drug and should be thought of as such. The only reason this compound is legal is due to the fact that it was never scheduled as a steroid since it was never manufactured, although its chemical structure is very similar to oral Primobolan. Users of methyl 1-test should be on the lookout for increased liver values, high blood pressure, extreme lethargy and pumps, as well as decreased appetite. Methyl 1-test should definintely be stacked with 4AD to help counteract some of these sides and give you the benefits of testosterone supplementation. Users should get blood work done before and after cycles of this compound. A cycle of methyl 1-test should not last any longer than 6 weeks. However, most users seem to prefer the 2 weeks on/2 weeks off pattern. Estra-4,9-diene-3,17-dione (Finagenx) This is a relatively new compound on the market. The manufacturer claims that this is a precursor to the powerful steroid trenbolone, however this does not seem to be the case. It does appear to convert to a steroid hormone, but it is not tren. It is a dione so you will have some conversion to estrogen even before it converts to its parent hormone. It is unknown what the anabolic/androgenic ratio of its parent hormone is, how it acts in the body, or if it can aromatize or not. This is a very expensive compound for the amount of gains users are reporting. The dosing seems to be very high, although I am not sure of the dosing pattern at this point. I would personally avoid this product. It is too expensive, with very little feedback. A methylated version of this compound should be out soon and sounds promising. Hydroxy Testosterone This testosterone has come on the market recently in the form of transdermals and powder. It is actually nothing like its parent other than the name. It is very mild in terms of anabolic and androgenic potential and would be relatively weak on its own. However, this compound has some very interesting attributes that make it very different from all the other steroids on the market. With the 4 hydroxl position on the molecule, it has the added benefit of not converting to estrogen or DHT. This would make it very similar to the compound Clostebol and ideal for cutting when used on its own. It also has the very interesting attribute of being a mild aromatize inhibitor and 5AR inhibitor (which prevents conversion of testosterone to DHT). One of its metabolites is Formastane (4 hydroxy androstenedione) which is also an aromatize inhibitor. It has also been claimed that this compound will stimulate LH output, which would be great for bridging inbetween cycles and obviously not cause any form of supression. However, I have not seen any data to confirm this. This compound appears to be very weak on its own. With the high price per gram for the powder, it would be a poor choice to use on its own. It does stack well with any other compounds, and like everything else would be optimally used with 4AD where it would impart very lean gains with virtually no sides. Since this is such a new compound, I really have no idea on what the dosing pattern would be. I would expect to see a methylated version of this on the market soon. As with all other steroids, this would be a very poor oral compound. It would probably be best used transdermally. Making it into an injectable seems to be very troublesome, as it is not very oil soluble without an ester. Hydroxy Nandrolone This compound is the same as a steroid known as Oxabolone which has been off the market for years. It has the attributes of being quite anabolic and not very androgenic. It cannot make the conversion to DHN, which is a relatively weak on its own anyway. It has also been speculated that this steroid acts as an aromatize inhibitor, like Hydroxy Testosterone, but I have seen no evidence for this either. Most information on this steroid seems to be speculation. Since it is a nandrolone derivative, it might have progesteronal activity. Also, since there is so little feedback on this compound it is hard to say. It would probably be similar to the popular steroid Deca, albeit weaker. It might make a closer match to trenbolone in activity, but there is little evidence to suggest that at this point. With the other compounds, any information on dosage is speculation at this point. A methylated compound known as 17aa 4OHN is soon to be replaced. I have heard claims that this should be similar to Anavar at an even lower dosage. However, this has not been released yet, so we will have to wait and see. As with all methylated compounds, one would want to take similar precautions when using these types of oral based steroids. Hydroxy Nandrolone is illegal in California and Nevada, but not federally schedulled. Methyl 5AA Another methylated version of an older prohormone, methyl 5AA should be a similar match to Proviron or Masteron. This compound will make a conversion to Methyl-DHT in the liver through the 3bHSD enzyme. It should be very well suited as a preworkout stimulant, as well as reducing the effects of estrogen and SHBG on a cycle. Since DHT acts as an aromatize inhibitor, it can help reduce circulating estrogen on a cycle in leu of typical anti-estrogens such as Nolvadex or 6OXO. Oral DHT has also been shown to bind to SHBG, allowing for more of other more powerful androgens to attach to the receptor, allowing for an overall more anabolic effect. One problem with DHT and its precursors is the fact that they are deactivated in skeletal muscle through the 3 alpha HD enzyme to prohormones like 5AA and 3 alpha. This seems to happen when an abundance of androgens exist, and is why DHT, even more potent than testosterone, does not make for a great muscle builder. Another concern for its users is the strong androgenic effets of DHT. This would obviously be a concern with individuals with potential prostate issues or androgenic alopecia. However, since this prohormone is making a conversion in the liver, instead of high 5AR saturated areas like the scalp and prostate, it would probably not have as many negative side effects as even typical 4AD/testosterone would. The dosage seems to be in the low range. Anywhere from 5-30mg anytime of day would work. It sounds like it would be particularly beneficial preworkout, where it would impart some of the positive benefits on neural activity, giving the user added aggression, energy and strength to have a better workout. As with all methylated compounds, similar precaution should be taken of not running the compound for more than 6 weeks and having blood work done to ensure the liver is in proper working function. Methyl 1,4diol Here we have a methylated version of the boldenone precursor, 1,4diol. In this version, the methylated version of the diol prohormone has been used instead of the dione. This will allow the hormone only direct conversion to its parent hormone, methylboldenone (Methandrostenolone) better known as Dianabol. Since this is a direct precursor to Dianabol, I would expect the same effects of it such as bloating, water retention and the high possibily of gyno. This is due to the fact that boldenone can aromatize into estrogen, here we would have a more powerful methylated estrogen, Methyl-estradiol. This would obviously be a very good mass builder, imparting gains in size and strength in a very short peroid of time. Obviously, quite a bit of it will be water though. Just as you would run Dianabol, you would want to stack it around 4AD/testosterone. You would want to have a good anti-estrogen on hand such as Nolvadex or Arimidex. Dosage for this compound has not been determined yet, but should probably be in the same range we've seen the other methylated prohormones. Again, you would not want to use this for more than 6 weeks and have blood work done once the cycle is completed. Methyl 4AD As if you didn't see this one coming, we now have a methylated version of our favorite prohormone, 4AD. The problem with this hormone, is it will directly convert to methyltestosterone, which is a very poor compound. Methyltestosterone will aromatize to methyl-estradiol and convert to methyl-DHT. The sides of these would obviously be much harsher than using its non methylated counterpart. The only positive effect I could see from methyl-4AD would be if it had instrinsic anabolic activity before conversion, which we have no idea about. The other good use for this would be as a preworkout boost, where we would have the added aggression and CNS stimulating effects of 4AD. Just using it preworkout would allow us to get the benefits, without the negatives, along with relatively no HPTA shutdown. Dosage for this compound has not been determined yet, but should probably be in the same range we've seen the other methylated prohormones. I have seen dosages recommended for 5-30mg daily. Again, you would not want to use this for more than 6 weeks and have blood work done once the cycle is completed. Products Not Yet on the Market I have added a few products I would expect to see out soon. Some of these may never come to light, but most probably will. So I decided to through them in anyway. Methyl Nordiol This compound should be fairly similar to the unpopular steroid Nilevar. Being a direct precursor to methyl-nandrolone, we would see increases in methyl-estradiol and methyl-DHN. Giving us a weak anabolic with more sides than we would expect from this weaker hormone. I would also expect there to be progestonal activity with this. So, although this seems to be another poor compound, it might have some good use in women or as a preworkout booster. Methyl Hydroxy Testosterone I would expect this to be similar to 17aa 4OHN. It will probably be very similar to Oral Turnibol where as it won't convert to estrogen or DHT, it will impart gains on strength and hardness, rather than mass gains. A Word About Methylated Compounds I feel we are now at the pinnacle of prohormone development. We now have prohormones/steroids that are methylated for almost complete bioavaibility. This is obviously a dream come true for individuals looking for true legal alternatives to illegal steroids. However, we need to realize that these are drugs in the true sense of the word. These can be very dangerous if misused or abused. It is imparitive that people think of these as drugs instead of typical OTC supplements that you can take lightly and not be concerned about possibly bodily harm. It is very easy to rationalize the fact that hepatoxicity doesn't happen, or that it happens in very minute amounts, but when we look at studies dealing with oral steroids we only have ones that we have seen on the market for years. With methyl 1-test and others, we have no idea if they are as hepatoxic as Halotestin or as mild as Proviron. It is always a good idea to get blood work done before and after a cycle to ensure that your liver is in proper health and you do not have underlying conditions that could be slowly killing you. Please be safe, and respect that these are powerful chemicals with potential to cause great gains as well as harm your body. A Word About Liver Protectants A lot of people have been using liver protectant supplements such as Silymarin and NAC to help protect their liver from damage when using methylated compounds. However, I feel that this is a bad idea. When you use compounds that increase gluthione levels in the liver, it will increase the breakdown of oral drugs, making them less effective. Although increasing liver enzymes is good for your liver, it is bad for any drugs you want to take and allow them to pass through your liver unabated. A better idea would be to use liver protectant supplements before and after a cycle to help your liver rebuild its enzymes after they have been damaged by methylated compounds. I have no idea if using liver protectants on a cycle will inhibit gains in any significant degree, but it could. Keep that in mind when planning your cycle. ---------------------------------------------------------------------------------------------- I really hate to write out another preacher post, but I feel it just has to be done. This is a total rant on my part, so please keep that in mind while reading this. I am bombarded daily with the same questions over and over. These people ademantly refuse to follow any sort of advice or guidelines to using prohormones. Some of this can also be used for steroids and in fact most supplements in general for beginners. So, lets get started. Eligibility of using Prohormones Using prohormones is not for everyone. In fact, most people shouldn't use prohormones. I am not going to make the call for people to whether or not one should be able to use prohormones, because that is not my place. What I am suggesting is a general guideline to make sure you are ready for using prohormones as an individual, and as a bodybuilder. So, here are the rules: 1) If you have been training for less than a year YOU SHOULD NOT USE PROHORMONES. This is very simple. You need to have some experience in proper training behind you before you start supplementing with exogenous hormones. There is no reason to use them at this point in time, you can make great gains naturally. 2) If you are under 21 YOU SHOULD NOT USE PROHORMONES. This argument I have with people everyday. I tell people "You should not use prohormones under 21." Always the response is "Okay, so what prohormone would be the safest?". WRONG ANSWER, you should not be using prohormones!!! It is that simple. There is not a "safest" one for you, there are none. I am sick and tired of crybaby teenagers asking me how to use prohormones. Go pick up some creatine and leave prohormones for someone else. Still not convinced? Read this: Teenagers and Prohormones/Steroids 3) If you do not eat sufficient calories (ie: 6 meals a day) to gain naturally YOU SHOULD NOT USE PROHORMONES. This is so important. Diet is the key to bodybuilding. You could train all you want, but if you're not eating, you're not going to add the size you want. Please, buy a cookbook, get some protein powder, do whatever it takes to get those calories. 4) If you do not get at least 8 hours of sleep at night YOU SHOULD NOT BE USING PROHORMONES. Proper rest is essential to building a better body. Probably more important than most people realize. If you are not getting enough sleep, don't waste your time with hormones. 5) If you want to drink beer, use recreational drugs, party all the time, etc YOU SHOULD NOT BE USING PROHORMONES. If you are drinking more than once a week, don't waste your time. You need to make a determination for yourself what your goals are. If your goals are to be drunk everyday, then more power to you. But don't take prohormones in the misguided since that they will help you stay "anti-catabolic" or some bull****. I know its hard when your friends want to go and drink all the time, but sometimes you have to make a choice. 6) If you have a previous medical condition such as heart problems, diabetes, enlarged prostate, or other potential life threatening ailments YOU SHOULD NOT BE USING PROHORMONES. We have no clue about the long term effects of prohormones. People who use them are using them at their own risk in hopes of bettering themselves, but making muscle should not make you at risk for killing or seriously injuring yourself. Take a step back and decide what is more important to you: your long term health, or some muscle? 7) If you are concerned about potential side effects from estrogen or DHT YOU SHOULD NOT BE USING PROHORMONES. This is more for the people who say "what is the best prohormone without side effects?". Very dumb question. There is no such thing. Estrogen and DHT play a major role in gains, and if you don't understand that, then you shouldn't be using these substances. Part of the enjoyment of using prohormones should be understanding how they work in your body, so you can taper them for your own needs. If you say "I'm scared of estrogen" then don't use prohormones. All of them can potentially increase estrogen. Sorry, thats just the way it is. You can always take ancilleries, but if you are asking this question, you obviously didn't know that. 8) If you can only buy stuff from GNC YOU SHOULD NOT BE USING PROHORMONES. Get a credit card, genuis. Ruin your credit? Find a site that excepts money orders. There is absolutely no excuse for shopping at GNC. Don't complain that you can't order stuff from the internet because you live in Siberia or ruined your credit, or your mommie won't let you use her credit card. Either buy them from a reputable online company or don't buy them at all. You will get stuck with a ****ty product or pay so much damn money, you might as well just go get pec implants. 9) If you weight 150lbs or under YOU SHOULD NOT BE USING PROHORMONES. You have not gained enough naturally yet, or have enough experience in diet or training to justify exogenous hormone use. Please review your diet and training. If you have to say the following things to justify your use of prohormones, you should not be using them: I cannot eat enough because of _______. I cannot train properly because of _______. I cannot get enough sleep because of _______. I am younger than 21. I am concerned about the _______ side effect of prohormones, so I want to use something that is free of side effects. YOU SHOULD NOT BE USING PROHORMONES I feel for you, and understand your situation, but the fact remains. Just because you are trying to accomodate your poor workouts and diet with prohormones is not going to work. Learn how to eat, sleep, and workout properly FIRST. Now, if you have passed the first part, you are doing good. You make the bear minimum to quality for using prohormones. Congradulations, have a cookie. Planning your cycle This is the next important part of using prohormones. Don't run out to GNC and buy the first bottle that says "Testosterone Booster" on the label, or what your buddy at the gym said he took to get "jacked up". Don't be a dumb consumer. Read up, and figure out what you want. Don't get stuck on one thing or another just because you heard it was good, or you are scared of a certain side effect. Read through this site, and others looking for feedback on particular products. This is also key: UNDERSTAND HOW STEROID HORMONES WORK. Please read about how people plan steroid cycles, and how steroid hormones work in the body. Prohormones are just precursors to steroids, so we try and plan cycles out similar to them. Read all you can. Take the time out to learn what you put in your body and how its going to effect you. Don't be a neglegent idiot and take something without understanding it, because you will reap the consequences. Maybe not now, or even if you do cycles later, but something will happen. It always does. So, here are the rules for using prohormones properly. 1) Plan out your cycle before you purchase. If you just run out and buy something for the sake of buying it, you are going to get stuck with using it. A lot of people come to me and ask "How can I use 100mg of nordiol caps?" The answer is simple. You can throw them in the garbage or sell them on eBay. Don't waste your time with very low dose orals or products containg andro, 5AD or DHEA. Also, don't use products that contain herbs like tribulus or chrysin. They are not effective at doing **** except draining your wallet. Stick with well known, good products. If you were thinking of buying a product like that, stop and go back over the first part of the post or read the Prohormone FAQ. 2) Buy some Nolvadex. This is simple. Buy some Nolvadex. Can't get it? Don't use prohormones. Very simple. The reasons for having this available to you should be obvious. If you don't know why you need Nolvadex, you shouldn't be using prohormones. 3) Decide which side effects concern you most, and plan your cycle around that. Concerned with hairloss? Use nordiol. Concerned with prostate enlargement? Use nordiol. Concerned with acne? Hey, I hear if you go to the grocery store they have this great new stuff called SOAP. If you have serious acne and can't stand any more, don't use prohormones. Starting to get the picture? If you want to use a compound void of most side effects, nordiol is your best bet. 1,4andro is the next best. It's really easy to get caught up in being scared by side effects, but if you understand how steroid hormones work, you will realize that there are no such things as side effects, they are just mechanisms of the hormones. Buy ancilleries for side effects you are concerned about. Such as spironolactone for hair loss, or Nolvadex for estrogen problems. 4) Always use 4AD on a cycle. But you just said if I was concerned about side effects to use nordiol-- SHUT UP! Always use 4AD on a cycle, even if its a small amount. Some people are going to disagree with me here, but this is the best way to use prohormones. Plan your cycle around 4AD like a steroid user will do a cycle around testosterone. Same principle, applies here also. 5) Plan your diet and training around your prohormone use. Plan ahead, decide what you're going to eat and how you're going to train. This is pretty obvious to most, since they want to get the most out of their prohormones. Well, thats about it. Remember: you don't have to use prohormones. You can make gains without them, in fact you can make gains quickly without them if you dedicate yourself to doing it. Don't jump into prohormones without all the knowledge you can get. This is a modified version of my steroids post in the supplements forum, geared for people to use steroids. The ideals are essentially the same. This is basically for very new beginners, and some things in here people might disagree with or have varying opinions about, but its pretty basic info and I think it should be obvious to most, but for the sake of some people who don't know this, I am posting this. I hope it helps. I am bombarded daily with the same questions over and over. These people ademantly refuse to follow any sort of advice or guidelines to using steroids. So, lets get started. Eligibility of using Steroids Using steroids is not for everyone. In fact, most people shouldn't use steroids. I am not going to make the call for people to whether or not one should be able to use steroids, because that is not my place. What I am suggesting is a general guideline to make sure you are ready for using steroids as an individual, and as a bodybuilder. So, here are the rules: 1) If you have been training for less than 2-3 years YOU SHOULD NOT USE STEROIDS. This is very simple. You need to have some experience in proper training behind you before you start supplementing with exogenous hormones. There is no reason to use them at this point in time, you can make great gains naturally. 2) If you are under 21 YOU SHOULD NOT USE STEROIDS. This argument I have with people everyday. I tell people "You should not use steroids under 21." Always the response is "Okay, so what steroid would be the safest?". WRONG ANSWER, you should not be using steroids!!! It is that simple. There is not a "safest" one for you, there are none. I am sick and tired of crybaby teenagers asking me how to use steroids. Go pick up some creatine and leave steroids for someone else. Still not convinced? Read this: Teenagers and steroids/Steroids 3) If you do not eat sufficient calories (ie: 6 meals a day) to gain naturally YOU SHOULD NOT USE STEROIDS. This is so important. Diet is the key to bodybuilding. You could train all you want, but if you're not eating, you're not going to add the size you want. Please, buy a cookbook, get some protein powder, do whatever it takes to get those calories. 4) If you do not get at least 8 hours of sleep at night YOU SHOULD NOT BE USING STEROIDS. Proper rest is essential to building a better body. Probably more important than most people realize. If you are not getting enough sleep, don't waste your time with hormones. 5) If you want to drink beer, use recreational drugs, party all the time, etc YOU SHOULD NOT BE USING STEROIDS. If you are drinking more than once a week, don't waste your time. You need to make a determination for yourself what your goals are. If your goals are to be drunk everyday, then more power to you. But don't take steroids in the misguided since that they will help you stay "anti-catabolic" or some bull****. I know its hard when your friends want to go and drink all the time, but sometimes you have to make a choice. 6) If you have a previous medical condition such as heart problems, diabetes, enlarged prostate, or other potential life threatening ailments YOU SHOULD NOT BE USING STEROIDS. People who use them are using them at their own risk in hopes of bettering themselves, but making muscle should not make you at risk for killing or seriously injuring yourself. Take a step back and decide what is more important to you: your long term health, or some muscle? 7) If you are concerned about potential side effects from estrogen or DHT YOU SHOULD NOT BE USING STEROIDS. This is more for the people who say "what is the best steroid without side effects?". Very dumb question. There is no such thing. Estrogen and DHT play a major role in gains, and if you don't understand that, then you shouldn't be using these substances. Part of the enjoyment of using steroids should be understanding how they work in your body, so you can taper them for your own needs. If you say "I'm scared of estrogen" then don't use steroids. All of them can potentially increase estrogen. Sorry, thats just the way it is. You can always take ancilleries, but if you are asking this question, you obviously didn't know that. 8) If you do not have a source that has the available steroids that you want, then wait until you find a proper source. There are some good products for beginners, such as longer esters that don't need to be injected daily. Some things are best suited after you have several cycles under your belt. If you cannot find what you're looking for, be patient and wait until you find a proper source that has what you're looking for. Don't make do with subpar products or cycles that you don't want to run. 9) If you weight 180lbs or under YOU SHOULD NOT BE USING STEROIDS. You have not gained enough naturally yet, or have enough experience in diet or training to justify exogenous hormone use. Please review your diet and training. If you have to say the following things to justify your use of steroids, you should not be using them: I cannot eat enough because of _______. I cannot train properly because of _______. I cannot get enough sleep because of _______. I am younger than 21. I am concerned about the _______ side effect of steroids, so I want to use something that is free of side effects. YOU SHOULD NOT BE USING STEROIDS I feel for you, and understand your situation, but the fact remains. Just because you are trying to accomodate your poor workouts and diet with steroids is not going to work. Learn how to eat, sleep, and workout properly FIRST. Now, if you have passed the first part, you are doing good. You make the bear minimum to quality for using steroids. Congradulations, have a cookie.
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Planning your cycle
This is the next important part of using steroids. Decide what cycle you want to do and review it with the other board members. Don't just take Winstrol or Dianabol by itself because that is only what your source has, or what your buddy at the gym said he took to get "jacked up". Don't be a dumb consumer. You are paying a lot of money for these substances, so be aware of what you want, including brands and quanity. Read up, and figure out what you want. Don't get stuck on one thing or another just because you heard it was good, or you are scared of a certain side effect. Read through this site, and others looking for feedback on certain cycles. This is also key: UNDERSTAND HOW STEROID HORMONES WORK. Please read about how people plan steroid cycles, and how steroid hormones work in the body. Read all you can. Take the time out to learn what you put in your body and how its going to effect you. Don't be a neglegent idiot and take something without understanding it, because you will reap the consequences. Maybe not now, or even if you do cycles later, but something will happen. It always does. Also, read through the FAQ, Steroid Profiles and Best of Section. Do a search for what you are thinking of running. Ask intelligent questions based on research you have done yourself. So, here are the rules for using steroids properly. 1) Plan out your cycle before you purchase. If you just run out and buy something for the sake of buying it, you are going to get stuck with using it. A lot of people ask "How can I run a cycle using Winstrol or Dianabol only?" The answer is simple. You don't. Don't waste your time with oral only cycles. Plan out a proper cycle with injectable steroids, or don't do one at all. If you want to test the waters and see how you do, then you could possibly run a cycle of Anavar or something for 2 weeks to see how you react, but I really wouldn't bother. 2) Always have ancilleries on hand. This is simple. Buy some Nolvadex & finasteride. The finasteride is optional, but don't get caught experiencing side effects and not having ancilleries around. Your source should always be able to get you ancilleries, so this really shouldn't be an issue. The reasons for having this available to you should be obvious. If you don't know why you need Nolvadex, you shouldn't be using steroids. 3) Always use testosterone on a cycle. This should be fairly simple. Testosterone should be the base of any cycle, always. Testosterone gives us the best gains, while leveraging out the side effects. Don't be concerned about "estrogen" or "DHT" because that is the ignorant way to view it. If you are concerned about side effects, then have the proper ancilleries on hand for that occasion. 4) Plan your diet and training around your steroids use. Plan ahead, decide what you're going to eat and how you're going to train. This is pretty obvious to most, since they want to get the most out of their steroids. 5) Always use HCG post cycle. This is a must. HCG will allow you to bring your nuts back. Even on milder cycles, HCG should always be used with Clomid or Nolvadex. Well, thats about it. Remember: you don't have to use steroids. You can make gains without them, in fact you can make gains quickly without them if you dedicate yourself to doing it. Don't jump into steroids without all the knowledge you can get. Comments are welcome. --------------------------------------------------------------------------------------------------------- 1. Transdermal basics Q: What is transdermal delivery? Transdermal delivery is a method of delivering active drugs through the skin barrier, and is in many cases superior to other forms of delivery (oral, sublingual, etc). It involves applying active substances (such as prohormones) dissolved in a carrier (a substance or blend of substances designed to promote delivery of the active ingredient past the skin barrier). Q: Why is transdermal administration of prohormones superior to oral administration? There are numerous reasons why transdermal delivery can be preferable. The first is that transdermal delivery allows prohormones to avoid first pass metabolism in the liver. Most prohormones are readily destroyed in the digestive tract and liver, often making the dosages required (and money spent) much higher compared to transdermal delivery. It is estimated that transdermal prohormones have a 30-40% absorption rate, compared to 5-15% for oral prohormones. Also, certain hormonal substances may be toxic to the liver, and transdermal delivery significantly lessens this. Secondly, orally delivered prohormones have very short half-lives and must be taken 3-4 times daily. Not only is this inconvenient, but it means that during certain periods (such as sleep) blood levels of the hormone will be very low. Transdermal delivery effectively leads to a steady release over 12 or more hours, solving both of these problems. Q: What are the advantages and disadvantages of transdermal administration of prohormones when compared to sublingual/nasal administration? Sublingual (absorption in the mouth, like a lozenge) and nasal delivery is limited by the amount that can be absorbed by the mucous membranes. The maximum amount of hormone that can be delivered is around 25 mg, and blood levels are elevated for 2-3 hours, compared to ~12 for transdermal. Therefore, sublingual and nasal prohormones must be dosed at least 5 times a day to be effective. However, sublingual/nasal delivery delivers 80-90% of the actives to the bloodstream, making it a very efficient carrier. A combination of transdermal application (for steady blood levels) and sublingual/nasal application (to spike blood levels, particularly pre-workout) could be effective. Q: If I apply a transdermal hormone to a certain muscle group, does it increase strength in that particular muscle group? Transdermal prohormones are delivered systemically, so applying them to a particular area will not cause disproportionate strength gain in that area. The exception is products that are geared toward local delivery, such as Sytenhance. Q: Should transdermal prohormones be cycled differently than oral prohormones? Cycles with transdermal prohormones should be the same length as one would use with oral prohormones, and post-cycle recovery should remain the same. The primary differences are how often you will administer the prohormone (two times daily as opposed to three or four) and the dose used. Q: What are the dosages for transdermally administered hormones? First off, it should be noted that the listed dosage and duration on product labels is often conservative. Also, dosage will vary on stacking, level of experience, and many other factors. Here are some general guidelines 1-testosterone: 200-500 mg 19-norandrostenediol: 400-800 mg 4-androstenediol: 400-600 mg 3-alpha androstenediol: 50-150 mg 3-beta androstenediol: 200-500 mg 4-hydroxyandrostenedione (formestane): 50-200 mg androstenetrione (6-OXO): 150-500 mg 7-OXO-DHEA (7-Keto): 100 mg Note: Much of the dosage information comes from the prohormone FAQ, by pogue. Q: What are the differences between the Dermabolics carrier and other carriers? The Dermabolics carrier is identical to the carrier developed by Avant Labs except it does not contain carbomer, a thickening agent (due to the fact that it is a spray instead of a lotion). For a discussion of the science behind this carrier as well as comparison to some other products, see Battle of the Transdermal Prohormones by Par Deus. 2. Application tips Q: When, where and how should transdermals be applied? Transdermals should be applied as close to twelve hours apart as possible. An ideal time to apply is after showering or bathing. Scrubbing with a luffa, wash cloth, or sponge beforehand improves delivery, as does shaving the area of application. Ideal areas of application are those with thin skin, such as wrists, top of feet, upper arms, chest, back, or legs. Larger amounts will require larger application areas. If possible, latex gloves should be worn during application. These can be purchased at most pharmacies. It is also a good idea to shake the bottle before application to mix the ingredients. Spray or pump the lotion onto the hand and then rub into the application area. Afterwards, wash your hands with soap. Five minutes should be allowed for the transdermal to dry after contact with clothes or other objects. Q: After applying the transdermal, should I wait before working out, showering, or swimming? Yes. Water can wash off the transdermals making them less effective. You should wait at least half an hour before any of these activities, and ideally 1-2 hours. Also if you shower after application it is best not to scrub the area of application. Q: Should I avoid contact with other people in the area of application? Most definitely, especially females and children. This applies primarily if you are using a prohormone or steroid. Contact with the area may result in delivery of active hormone to the person contacted. If you think it will become a problem, it is best to keep the area covered (saran wrap over the area of application will work), or only use areas that will be covered with clothing as application spots. Also, certain application areas (such as the back of the legs) are less likely to be contacted. Q: My transdermal product is resulting in rash/skin irritation. Is this normal? How do I avoid this? Some people experience skin irritation or rashes from transdermals, especially those containing certain active ingredients. 1-testosterone is particularly caustic, and latex gloves are a must when applying this substance (even after washing hands thoroughly small amounts can remain that may get in the eyes or other sensitive areas, and it is quite painful). If latex gloves are not available, you can at least use a sandwich bag. The best way to avoid irritation regardless of the source is to rotate the area of application – one day apply to the feet, another to the upper arms, and so on. You can also apply lotion to areas of application not in use. 3. Homebrewing Q: Can I add more prohormones to a transdermal prohormone product? Yes, but it will become saturated at a certain point. Also, increasing the concentration may reduce the relative effectiveness. If you want a concentration or blend of ingredients that is not available pre-made it is usually better to make your own using a carrier product such as the transport matrix. Q: How do I make my own transdermal prohormone? Simply add the hormone powder to the carrier and then shake. If you accidentally put in too much hormone powder heating lightly and shaking vigorously may help. To heat a solution, boil a pot of water and let it cool to just below boiling. Place the prohormone bottle in the water for a few minutes, remove, then shake. Q: I am using the Dermabolics carrier. Can adding DMSO increase the efficacy of my transdermal prohormone? This carrier is quite effective as it is. In theory, adding 5-10% DMSO may increase absorption. However, one will have to put up with the side effects of DMSO (increased irritation, bad breath, etc). 4. Miscellaneous Q: Can transdermal prohormones be dosed more often than two times daily? If desired, a smaller dose can be used three times daily (every eight hours), but this does not have a clear benefit. Q: Is it acceptable to use transdermal prohormones in conjunction with topical fat loss products? Yes, just avoid applying them both in the same area. Q: Can transdermal prohormones be used along with oral prohormones? Yes, although if one is doing an intraday cycle (oral prohormones during the day, transdermal overnight) trying to compare oral and transdermal doses can often be difficult. Stacking one prohormone transdermally and another orally is not uncommon. Q: What is the shelf life of transdermal prohormones? This depends on the substance; in general the shelf life is 1-2 years. This can be increased by freezing and/or vacuum sealing. If you are planning on stocking up you are better off buying bulk prohormone powders and then mixing them in a carrier before use. By David Tolson - Special thanks to fuzz and the members of the Avant Labs forums for helping with this FAQ. ------------------------------------------------------------------------------------------------------- Other useful links - PART ONE: intro to PHs, explains PH sides, older PHs like andro and 19-nor, 4-AD, 1-AD, 1,4-andro, delivery options, dosing, and FAQs. PART TWO: explains the conversions of PHs (ie. 4-AD to test and 1-AD to 1-TEST). PART THREE: just a good read. read these and you will be well on your way to understanding the process of PHs.... Normal Values For Blood Testing Testosterone: (normal range 300 - 1200ng/dl) Free testosterone: (normal range 8.7 - 25pg/ml) IGF-1: (normal range 109-284ng/ml) Estradiol: (normal range 5 - 53pg/ml for adult male) DHEA-s: (normal range 120 - 520ug/dl) Thyroid panel T4: (normal range 4.5 - 12ug/dl) T3: (normal range 2.3 - 4.2pg/ml) TSH: (0.350 - 5.500uIU/ml) Total cholesterol: (normal healthy range 100 - 199mg/dl) LDL fraction: (normal range 0 - 99mg/dl) HDL fraction: (normal range 40 - 59mg/dl) Triglycerides: (normal range 0 - 149mg/dl) C-reactive protein: (>2mg/l increased risk of MI and stroke) Homocysteine: (normal range 6.3 - 15umol/L) Alkaline phosphatase: (Normal range (25 - 150IU/L) GGT: (normal range 0 - 65IU/L) SGOT: (normal range 0 - 40IU/L) SGPT: (normal range 0-40IU/L) PSA: (normal 0.0 - 4.0ng/ml) Creatinine: (normal 0.5 - 1.5mg/dl) BUN: (normal range 5 - 26mg/dl) Creatinine/BUN ratio: (normal 8 - 27)
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Spot Injection Techniques
Written by Sledge I have noticed that there are a lot of posts about site injections that lack important information. After reading them and talking with a couple friends on this subject, I decided that an article might help to clear up a few things. Some common questions are: What gauge needle should on use on which muscle? How many mls should I start with? What areas can I shoot?, What do I do if I hit a vein? You might notice that some of the things that I say will be different then the advice you get from others. This won't be first time that I don't agree with the other experts and I am sure it isn't the last. I am not claiming that they are wrong and I am always right, but I do have a lot of experience when it comes to spot injections. I would like to share with you the techniques that I have used. Sterility should be your first concern because you don’t want to get an infection or an abscess. Most people feel hitting a nerve or a vein is the first thing to worry about, it isn’t. Although I will discuss what to do if you hit a vein or a nerve later, if you get an infection or abscess you need to see your doctor and get it drained, go on a course of antibiotics and depending on the size of the abscess get it drained and possibly cut off. You definitely don’t want an oozing lump of infection on top of your bicep. There are different procedures to use depending if you use a single dose amp or a multi-dose vial, I will discuss both of them. All amps of steroids contain some amount of benzyl alcohol (BA) to help keep the product free of most of bacteria; this doesn’t mean that they are all sterile. Mexican steroids usually contain less BA and have more bacteria so don’t assume your oil is perfectly clean. Always make sure your hands are clean before you do any injecting as well as making sure you have all of your needles and alcohol swabs ready before you start. Multi-use amp: First you will want to hold your amp under warm water from the sink, this helps kill some surface bacteria as well as heating the oil slightly which will make drawing it and shooting it much easier. You only want it to be warm water if the water is too hot you can actually burn your muscle if you inject oil that is too hot. Then you use rubbing alcohol or isopropyl alcohol to clean the rubber stopper of the amp. Then using a 16g x 1.5 inch needle draw the amount of oil you are going to be injecting into the syringe. Now take the 16g needle off and switch to your shooting needle, the size will depend on what part you will be injecting into. Single dose amp: These need to be cracked open, you can use an actual amp saw to score the top neck of the amp and then crack it off, the best way that I have found is use the top of a pen cap, place the pen cap over the top of the amp and snap it off. Using the same technique as above you will use a 16g needle and then switch to your shooting needle. Ok, now the oil is in the syringe, you have your shooting needle on and you are ready to shoot, we will start with: Traps: Use 23g x 1.5”needles. Start with 1.5cc work up to 3.5cc When shooting into the traps you need to be careful of the veins and nerves that run up the side of the neck to the head, also starting with to much oil in this spot can cause a lot of neck pain. So start small and work your way up as you will with all of these injections. Start with 1.5 cc per Trap. When site injecting whether its for growth or swelling (there is no real scientific evidence that site injecting causes actual growth of the muscle tissue, although I feel it does and my triceps have defiantly gotten bigger since I started site injecting.) you need to keep balance between the right muscle and the left muscle, so make sure the amounts injected is even to both sides. When looking in a mirror you want to inject mid way on your trap between your shoulder and your neck, and slightly to the back side of your body. When you inject, I go slow, I know a lot of people suggest going fast, it seems that most people tense too much when shooting so by going slowly you don’t tense and there is less bruising to the area. After breaking the skin and slowly pushing the needle in all the way, you pull back on the plunger to aspirate, you don’t need to pull all the way back till you have bubbles floating in the oil, you only need to have a slight vacuum. If there is a slight vacuum or a bubble you are ok, if you hit a vein blood will come into the syringe, it’s not a big deal pull the needle out and move to another spot. If you hit a nerve it feels like a tingle and you will see the nerve make the muscle twitch, it’s uncomfortable so just pull the needle out and again start in another spot. Don’t mistake the twitch of a muscle because you aren’t relaxing. You need to keep your muscles relaxed when you site inject especially if it is a new spot for you. Now slowly inject the oil into the trap, do a 1/4cc at a time then wait a few seconds and continue till it is all in. Now when pulling the needle out pull ¼ of it out wait a few seconds twist slightly and then pull another ¼ out wait a few seconds and continue till it is completely pulled out. By waiting a few seconds you give the oil a chance to fill the space of the needle and you should minimize the amount of oil or blood that will leak out of the injection site. This will be the same procedure for all muscle groups. Deltoids: 25g x 1” or 23g x 1” Start with 1cc work up to 2.5cc. All three heads of the delts can be injected into, although you will need help for the rear delt, the side and front delt shouldn’t be a problem. When injecting into the front delt you need to be careful of the main vein that runs up the center of the arm from the bicep. You should be able to feel around on the delt and when you hit the vein you should actually see it pulse under the skin, obviously you want to be either to the right or left of the vein. Again follow the same procedure as above and pierce the skin slowly and push the needle in slowly, you shouldn’t hit any nerves but like I said the vein is possible so just take things slowly. For the side head there aren’t any surface veins to worry about, but you can inject two different ways, straight into the side of the head and down from the top. If you inject down from the top it looks more natural as the oil will push the muscle up, in from the side makes the side head actually stand out. Follow the same procedure for injecting. Biceps: 25g x 1”, 25g x 5/8”, 23g x 1” Start with 1 cc work up to 2cc. The two heads of the biceps can be used although it is easier to shoot into the inside head, the procedure is slightly different for the bicep. What you do is flex and mark the spot of the peak of the bicep, now straighten your arm and relax the muscle, where you marked it is where you inject just to the inside or the outside of the main vein. Although it looks like you are injecting to high on the muscle you aren’t, you want to inject deep enough though to push the head of the muscle up not have the oil sit on the top of the muscle, which will look like a lump instead of a bigger muscle. Triceps: 25g x 1”, 25g x 5/8”, 23g x 1” Start with 1 cc work up to 2 cc. Even though there are 3 heads of the triceps you will only be injecting into 2 of them, the inner and outer head, not the head nearest the elbow. For the outer head you can use the 5/8 inch needle, again you will want to flex the tricep and inject in the thickest part of the head, shooting when relaxed of course. For the back head you can inject in two different spots, the thick area where the arm touches the side of the lats or the upper most part of the tricep. For the back part you need to be careful of the nerves and veins that run through this area of the arm, again injecting slowly does help here. When going into the top part you will be on a slight angle and injecting actually behind the head, this will help give a more dramatic look as well as extra shape. Chest: 23g x 1”, 25g x 1” Start with 1cc work up to 3 cc. The chest can be a very scary area to inject into especially with all of the horror stories of Milos Sarcev almost dying from injecting Synthol into his chest. There are 3 main areas that can be injected into the chest, the upper pecs which are injected on an angle, the middle pecs which are injected straight into and the side of the chest. The upper and middle chest shots give more thickness to the pecs, while the side injection gives more width. For the upper chest shot the needle goes in on an angle, almost like you are saying the pledge of allegiance, for this shot I use the 25g x 1” needle, you need to go in deep enough to get the oil in the muscle but not so deep that you are near any veins. For the middle shot you can use either needle, it will go in the direct middle of the chest, straight in. These shots do take some practice and of course you still need to follow all outlined directions and of course stay relaxed. Forearms: insulin needle. ¼-1/2 cc. For the forearm shots, I know you can use oil but I would suggest only using small amounts of either kynoselen or PGF2a, only because the muscle area is very small and you don’t want lumpy forearms. Since PGF2a and Kyno are both a thinner liquid much like insulin, it doesn’t require a bigger needle to be injected and the forearms are very sensitive so the smaller the better when it comes to these injections. You need to be careful of all of the veins that are running through your forearms, so having them pumped will make this a much easier process. There really is only 2 spots you can inject as far as I am concerned, either the top or the bottom of the forearm. Either spot requires you to be careful and slow going.
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The Superdrol writeup
Chemistry Effects Anabolic effects & dosing requirements Strength Athletic Performance Fluid retention Fat Psychological Effects Recovery Adverse effects Everything OK in there? Unwelcome Growth Unwelcome Losses Supplements Necessary Supplements? Optional supplements Implications and Stacks Cycle Length Stacking Cost/benefit analysis ![]() The Superdrol writeup Chemistry Superdrol (methasteron) is definitely not a prohormone: it is a very active form of a designer supplement. Superdrol gets its name from the fact that it is a super-saturated, or 2-reduced, form of Anadrol. Anadrol has a =C-OH at the 2nd position, and if this is totally saturated (reduced) with hydrogen, it gives -CH3. Another way to describe it is that it is a 2a-17a-dimethyl of drostanolone (Masteron). Masteron has a single methyl group at the 2nd position. Superdrol is a modification of this structure by adding another methyl group at the 17th position, like M1T or M-Dien. However you may wish to look at it, it is by this simple-looking transformation that Superdrol comes to occupy the sweet spot between the chemical natures of Anadrol and Masteron. Since it is already reduced at the 5th position, it cannot make estrogen. Progesterone is not an issue: perhaps 0.1% can aromatize, in theory. In fact, this compound should not have any major metabolites at all. Maybe a few hydroxylated adrenal metabolites, but only traces. It is basically excreted unchanged as the conjugated glucuronate. The extra electron density at the 2 makes Superdrol 2-3x as anabolic (mg for mg) than Anadrol. To borrow from the language of genetics, Superdrol is a fine example of hybrid vigor: it has only the best attributes of each, and none of the worst. This is a supplement designed to have it all. Anadrol/oxymetholone 17ß-hydroxy-2-hydroxymethylene-17a-methyl-5a-androstan-3-one Superdrol/methasteron 2a,17a-Dimethyl-17ß-hydroxy-5a-androstan-3-one Masteron/drostanolone 2a-methyl-17ß -hydroxy-5a-androstan-3-one Proviron/mesterolone 1a-methyl-17ß -hydroxy-5a-androstan-3-one Effects Anabolic effects & dosing requirements As fascinating as all this chemistry might be, you are probably much more interested in how well Superdrol is going to work. What you are going to gain, and how much it will take you to make these gains? The gains from Superdrol are very dry and lean, so numbers do not tell the whole story, but let us look at them nonetheless. According to the book values, Superdrol should be 20% as androgenic as the reference standard methyl-test, and 400-800% as anabolic, while M1T is 910-1600%, and Anadrol closer to 300%, while being twice as androgenic as Superdrol, mg for mg. So in theory, Superdrol should be half as anabolic as the same dosage of M1T, and 10-20% as androgenic. This would mean that it should take twice the dosage of Superdrol to match the anabolic effects of M1T, at which dosage its androgenic side-effects would be 20-40% of those from M1T. Fortunately in the case of Superdrol it exceeds in practice its theoretical promise. All testers – who were selected in part because of their experience with M1T – found that the muscle gains produced from Superdrol were no less than 2/3 of what a comparable dose of M1T would have given them. Moreover, they found very few side-effects to complain about. What this means for you is that you will need somewhere between 10 and 40mg of Superdrol per day. Period. There was, certainly, a desire to get this product to market before the ban, but because we were able to keep its chemistry secret, competition did not force it to be rushed, as was the case with M-Dien. Accordingly, proper testing was carried out, allowing us to determine real world dosing recommendations, not ballpark theoretical numbers. The following recommendations are honest and accurate: 10-15mg will be sufficient for beginners under 200lbs; 20-25mg for those advanced lifters under 200lbs, or for those above 200lbs but untrained; 30-35mg for men who have seriously trained themselves but are under 240lbs. For men who think they need to run a dose which falls between the use of whole capsules, one extra 10mg capsule can be taken before workouts, such that the weekly average is appropriate. as a rule of thumb, Superdrol will require 50% more of a dose than M1T to give you comparable gains in muscle. Any women who are entertaining the possibility of using Superdrol should reduce the weight to accord with their sex and their height, and then divide these dosages by a factor of no less than ten. Capsules will then have to be diluted in liquid to be measured accurately. For men, 40mg is a dose only for the very large or the true non-responders, by which I mean people who do not see results on less than 30mg of M1T. Very few people will need 40mg of Superdrol, and no one will need above 50mg. If used in a stack reduce the daily dose by 5-10mg, which would be very prudent given how well Superdrol will stack, and if not its expense, then your very limited supply. The testers whose dosing fit the above guidelines gained, on average, five pounds of muscle in under three weeks, while losing water and gaining no fat on hyper caloric bulking diets. The quality of the gains from Superdrol comes from its likeness to Masteron while the quantity comes from its similarity to Anadrol. Masteron, expensive and very rare, is almost a perfect cutting steroid, being highly androgenic and anti-estrogenic. If you must have a rough comparison to something already out there, one tester described the quality of gains as being akin to those from fina or a test/halo combo, but such comparisons are bound to be inexact. Gains are very dry, and it makes muscles noticeably more hard and dense. The explosive gains from Anadrol are accompanied by a great deal of water retention and fat. M1T, as you surely well know, produces explosive gains not unlike those of Anadrol, but this comes at a cost. More on this later. As to how difficult it is to retain the gains from Superdrol, you are invited to follow the testers’ post-cycle results. To date, the results are promising, with no loss of mass or vascularity. The gains from Superdrol will be impressive, and they will not take long to start, but they will be more gradual to be recognized than those which come from aromatizing steroids. Your numbers in the gym and on the tape measure will go up, not explosively, but they will go up surely and steadily. The diuretic effect of Superdrol will at first mask the gains as you lose water and gain muscle. When mass begins to increase, it should do so disproportionately compared to tape-measurements. So if you are only checking the scale, or if you are not lean enough to notice the loss of water, persist and be rewarded. Strength Anadrol is famous for explosive gains in strength. M1T is not. Superdrol shares with Anadrol a capacity for impressive, but consistent, gains in strength. Testers experienced dramatic and immediate strength gains, when consuming sufficient calories. To their surprise and our delight, every single one became stronger every single workout, and many personal bests were recorded, while volume increased. Being a DHT derivative, it is a fair question to ask whether the strength gains from Superdrol can be maintained, or whether they will not dissipate shortly after one terminates use of the drug. In response to this, consider that 1) the strength gains from pure androgens are not generally accompanied by proportional gains in mass, and 2) the gains in both strength and mass which result from dianabol/m1,4add are - besides being accompanied by bloating - diminished soon after one goes off, they don’t just disappear, but they are hard to keep. If the mass gains from Superdrol are solid rather than fleeting, then the strength which came with this increase in muscle mass should be much easier to maintain than those which can result from the use of Anadrol, Dianabol/M1,4ADD, or many of the pure androgens, which achieve a significant amount of their effect on strength through their psychotropic effects on focus and aggression. Athletic Performance Along with marked increases in strength, all testers observed undeniable increases in their endurance, whether in cardio or adding to the sets they could perform. Breathing and heart rates were not as high as expected. Given Superdrol’s chemical relation to Anadrol and Masteron, it was speculated that this could be due to an increase in red blood cell (RBC) count, which would allow the use of more oxygen. Masteron has also been used as an Anadrol alternative for aplastic anemia, so it should be a strong immune stimulator and RBC booster, as many 5-reduced compounds are. In Anadrol, the extra stamina which should accompany the known increase in RBC is largely counteracted by the estrogen related effects. Because these are absent with Superdrol, increased RBC count may seemed a probable explanation for the increase in endurance. But because the increased endurance occurred quickly, I am hesitant to assert that an increased RBC count is the reason. Shortly after this appears in print, there should be blood work available to confirm or deny this. No matter the explanation, Superdrol does increase endurance significantly. Fluid Retention Masteron and Anadrol are on the opposite ends of the spectrum in regards to fluid retention. In this regard, Superdrol lies close to Masteron, which – being unable either to convert to estrogen or mimic the effects of estrogen – has typically been used for reducing water retention while increasing muscle hardness and density. The rapid gains in mass caused by Anadrol involve not a little water retention: bloating is unavoidable, as with Dianabol/M1,4ADD. With Superdrol, there is no extra water retention. There is not even facial bloating. It forms no estrogen, so the renin-angiotensin-aldosterone (RAAS) system cannot be activated to cause any water retention. M1T has the unfortunate effect of causing water retention in the kidneys, which can be painful, and is definitely unhealthy. The pumps for which Anadrol is known are caused by an increase in the volume of blood, some of it RBC but much of it water. Blood pressure rises accordingly, and can lead to headaches, other forms of discomfort, or worse. The pumps from Superdrol could well be the result of the volumization of blood without the water gain, as noted above. It is in fact a mild diuretic. This helps contribute to the unmatched vascularity noticed in lean individuals. Because it dries you out, unless you are cutting for a reason, like a contest, you should increase your water intake accordingly. You can expect to drop at least several pounds of water in your first few days of use. From testers who monitored their blood pressure, there was no indication that it rose significantly, nor were there in others symptoms of high BP, for example, face turning beet red, or feeling nauseous after a few light sets. The pumps and increased vascularity from Superdrol are pleasant - “my biceps feel flexed when at rest” in the words of one tester. That is, until the dose is becomes too high, at which point Superdrol shares with Anadrol back pumps, cramps, or aches. These can inhibit workouts. At proper doses, these are fleeting, not unlike those from M1T, but not as severe. However, the tester who challenged the highest dose experienced such discomfort that he literally had to lay on the gym floor in between sets. It seems that Superdrol has a built in mechanism, harmless enough, to prevent its abuse. Fat Masteron is very effective in cutting cycles to reduce bodyfat; Anadrol does not mind putting on a few pounds ‘for the winter.’ Superdrol testers were all eating well, no one was cutting, and mass was going up faster than tape-measurements. It was wondered whether Superdrol exhibited fat-burning properties like tren. This can be discounted, and explained instead as a diuretic effect: testers size did not change dramatically because they lost water, while their muscles grew and became more dense. So in regard to fat, Superdrol falls right between Masteron and Anadrol: one could say that it neutral in terms of partitioning. When using Superdrol, fat will not magically melt away, but nor will it especially inhibit fat loss on a cut. It will not especially prime you for fat gains on a bulk, but if you do not watch your diet you can get fat. Psychological Effects The psychological effects of Anadrol and Masteron are noticeable, if not as pronounced as with some other DHT derivatives. It was not clear what, if any, psychological effects should have been expected from Superdrol, given how little its androgenic effects looked to be on paper. What the testers found, to begin with was that Superdrol felt “somatically clean,” meaning that there was zero sense of physical malaise or indisposition which is common to Anadrol and especially M1T. On the contrary, testers had a sense of physical well-being, a clean feeling of being ‘on’ – as distinct from the sure knowledge that one is growing, even if one doesn’t feel well, that one gets from M1T or Anadrol. This feeling was not as pronounced as with Dianabol. Psychologically, the following were attributed to the use of Superdrol: confidence, assertiveness, focus, increased libido, the need to do something, aggressiveness in the gym, a command mindset, and some irritability – especially upon ramping up to the next dosing level. One tester described the CNS stimulation he got from doing 30mg at once as being stronger than 50mg of M5, 32mg of M4OHN, or EC. Endurance and strength should be mentioned here as well, because while above I have offered physical explanations for them, some of this effect could well be psychological, in which case it would dissipate upon cessation of the use of Superdrol. There was some increase in appetite for some of the testers, a decrease for others; in either case this was not overwhelming. Recovery Recovery time on Superdrol was improved, slightly but noticeably - not on a par, however, with a similar dose of M1T, let alone Anadrol. In this light you should be reminded that the increases in strength which you will experience on Superdrol do not come with a proportional increase in the strength of connective tissue. So when using Superdrol, you should observe strict form in the gym or else you invites injury, which obviously defeats the purpose of any kind of performance enhancing agent.
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Adverse effects Across the board, testers were astounded by the virtual absence of unwelcome side-effects from Superdrol use. One tester, already balding, mentioned an occasional itchy scalp. The only exception to the clean bill given to Superdrol was noted earlier, lower back pain at excessive doses. This lack of side-effects can be attributed to Superdrol’s very low androgenic capacity and its anti-estrogenic effects. Everything OK in there? So what’s the catch, the bad news? From the provisional results, there does not seem to be any bad news. You should be sure to check the results of the testers’ blood work which will appear in their logs. If I were to speculate as to what could be most worrying, it would be if Superdrol lowered HDL (good cholesterol) levels into the single digits - something which M1T is very good at doing. As to hepatotoxicity, Superdrol is estimated to be more toxic than M4OHN, while far less toxic than M1T. The blood work will tell, but there was absolutely no indication from any of the testers, or from the chemistry of Superdrol, that it should be highly toxic. The unbearable back pumps which accompany excessive use of Superdrol effectively limits its potential for abuse. There were no indications of high blood pressure: headaches, nosebleeds, or anything of the sort. Testers were not fatigued or lightheaded, or any of the other symptoms of low blood sugar levels, as accompanies the use of M1T and Anadrol. Superdrol could still have some effect on this, however, and it something to keep in mind, especially if one will simultaneously be using Glucophase XR. Sleep was not interrupted, nor was it reported to be noticeably improved. Nausea and diarrhea were absent. Unwelcome Growth As stated earlier, Superdrol is a mild androgen, and anti-estrogenic. Testers found no occurrence of acne, excessive hair growth, indications of benign prostate hypertrophy (BPH). You will not want to brave the back cramps to take enough of this to make you have to begin to be worried about androgenic sides. At 40mg, one tester noticed a tendency to bruise more easily. Zero estrogen conversion with this one, because it's 5-reduced and A-ring alkylated on top of that. Binding to the aromatase enzyme, estrogen production will be reduced. Also, the parent compound (Masteron) is used exclusively as an anti-neoplastic for metastatic breast cancer, so Superdrol is a strong anti-e. Clearly, Superdrol is not progestational, it is non-aromatizable, and even anti-estrogenic. But this said, it is worth reminding you that no one is clear on what the reasons are for why people get gyno. It can occur even in people using substances with these characteristics. One tester thought he could be having some early symptoms of gyno, although on paper there is clearly no reason to suspect Superdrol contributed to this. The point to take from this is that it is imperative to always have nolvadex or generic tamoxifen citrate powder on hand to administer at the first notice of symptoms of gyno. Unwelcome Losses As has been stated, Superdrol is a mild androgen, and hair loss (androgenetic alopecia) should not be much of a concern if you are not very predisposed to it. Another concern, especially in light of the peoples’ experiences with M1T is the question of how hard Superdrol will shut you down. The testers ran Superdrol by itself, some of them at very high doses. Not one experienced anything to indicate anything like the severe degree of shutdown which almost immediately accompanies the use of M1T. That said, it is inconceivable that Superdrol can do what it does without affecting the HPTA axis, and PCT is always mandatory. Because Superdrol itself is mild in terms of shutdown, if you were to run it by itself, recovery with PCT should be quite easy. Most people, however, will elect to run Superdrol as part of a stack. Necessary Supplements? In the case of most oral steroids, legal or otherwise, there are a number of supplements which are not really optional. With M1T, everybody’s favorite, 4-AD is really not an option. Liver protection supplements are optional, or they are so only at your peril. And little can be done about perpetually low blood sugar levels, and single-digit HDL levels. Anti-e’s are not specifically necessary for most orals, used alone. With Superdrol, none of these supplements are necessary - and no letro, finasteride, or dex - because none of these side-effects are especially worrisome. The only potential exception is the HDL issue. All steroid use adversely affects HDL levels, but we need to be sure to know how safe Superdrol is in this regard. The results of the testers’ blood work will resolve this worry, or make people aware that this is an issue. In any case, the only thing which could be done about this would be to limit the length of one’s cycle. As mentioned above, supplements are necessary with every steroid for PCT, and Superdrol even though it is mild in terms of suppression is no exception. I mention this here in part to remind you of the possibility that research chemicals may become much more difficult to come across depending on what actions take place subsequent to the ban. With Superdrol, if anything is close to necessary, it would be general liver protection such as from K-R-ALA. Everything else is strictly optional, and can be used in a complementary stack Superdrol, not as something necessary to counter the deficiencies of the primary mass builder. A very minor issue which you should look for an answer is what the half-life of Superdrol is in the body. If it is short, this will call for dividing your daily dose rather than taking it all at once. If the half-life is longer, it would be an unnecessary inconvenience to do so. Implications and Stacks Cycle Length Because of the toxicity of Anadrol and M1T, it is highly imprudent to use these for more than four weeks at a higher dose, and six weeks at any dose. For Superdrol, toxicity is not a great concern – little more than with M4OHN. So long as the results of the blood work come back favorably, i.e. if the HDL cholesterol is not reduced to single digit levels after several weeks usage, Superdrol can safely be used for longer cycles than 4 weeks. Otherwise, it should be used only for short cycles, or for short parts of longer cycles – obviously not in succession with M1T. I mention these issues because one of the things most of the testers mentioned is that they feel like they could run Superdrol perpetually: “I can run this forever” - “No, you can’t.” This would obviously be a bad idea. Stacking Unlike Masteron, Superdrol obviously works very well on its own. Anadrol is very powerful, but the problems with its use are evident. If you happen to get a lot of Superdrol, you can surely use it to great effect on its own, but given its limited availability, to get the most out of your supply, you will probably want to use it as part of a stack. Superdrol should stack well with pretty much everything, apart from those things which it begs to be used in the place of: such as M1T, M14ADD, DBol, Anadrol or Halo. There should be no need to stack this with another methyl. The only things even to consider this would be mild substances like M4OHN or M5AA, for example. As a rule, if you can find a way not to stack methyls, make the right choice. A low transdermal dose of 3-alpha is a very powerful pure androgen which could take the place of M5AA or MDHT. For bulking cycles, a stack with anything which aromatizes will work very well: Test, EQ/1,4ADione, Nandrolone. A significant amount of mass gains come from the presence of estrogen. Estrogen also stimulates white blood cell production, aiding your immune system, having too little estrogen will predispose you to becoming sick. M1T flu anyone? For more of a lean bulk more limited aromatizers would work very well: 4AD/ester, 19Nordiol/ester, 1,4ADiol, Primo. For a major cut, a non-aromatizing choice is called for, such as very dry mass-builder and/or a pure-androgen to produce sick separation and vascularity: 1-Test/ester or 5aa/ester, 3-alpha, Masteron, or Tren. There are so many combinations, it is really up to you to look at what is available, decide what your goals are, and choose the most appropriate items. You simply need to choose a complementary combination with your budget and your goals in mind. Listed below are some examples, suggested in discussion with the testers. You should be able to discern their purpose. And there will surely be a good deal of discussion about potential stacks and their merits on the boards. Superdrol + 1-Test + 4-AD + pure androgen + M4OHN Superdrol + Test or Sledge Test Superdrol + 5AD + 3alpha Superdrol + 4-AD + MDHT + tren Superdrol + 4-AD + tren Superdrol + Test or 4-AD + Deca or Nordiol Superdrol + 1-Test or Fina + Test Superdrol + 1,4ADD/EQ or 19Nor/Deca or M4OHN Cost/benefit analysis “There’s no way it can replace M1T.” So says the conventional wisdom about every new legal anabolic since the introduction of this famous mass builder. New substances have come to the market, and it is true that none yet has replaced M1T. What is also true, outside of the most outlandish circus-vendor salesmanship, is that nothing which has come to market has made claims to be a serious mass-builder, a true challenger to M1T. M4OHN and M-dien have received a lot of bad press, not because they are useless, but because people were expecting them to be useful in a way they were not. The pure androgens M5AA, and recently MDHT, were never intended as mass builders, but for strength, aggression, hardening, and maybe some modest dry gains. 1-AD, being related to M1T was impressive in its own right, but its cost put this posh wonder beyond comparison with its inexpensive brethren. M1,4ADD could plausibly be called a bulker, but like its metabolite Dianabol, the gains from M1T by itself were more impressive and seemed qualitatively superior, even when M1,4ADD was used at an appropriately high dose. Superdrol is up against M1T. By now consumers of legal anabolics have accepted M1T as the bar by which all competitors are judged.
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N.B.O.L.T. Co-founder |
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Rebound XT
What is it? Rebound XT is an anti-aromatase/anti-estrogen that can be used on cycle, during post cycle therapy (PCT) or off cycle to control estrogen and raise testosterone naturally. What does it do? Rebound XT binds irreversibly to the site of the aromatase enzyme rendering it inactive. It is then unable to produce estrogen. By reducing estrogen production, the amount of estrogen circulating in the body is reduced and the amount of testosterone is increased indirectly. On cycle, Rebound XT is used as an anti-estrogen to prevent estrogen related side effects such as water retention and gyno. It also helps to combat the signs of existing gyno. During PCT, Rebound XT is used to control estrogen levels while boosting natural testosterone production. Off cycle, Rebound XT is used to maintain healthy levels of testosterone while still controlling estrogen. This is beneficial for men that suffer from decreasing levels of testosterone due to age and other factors. How do I use it? For maximal absorption, take Rebound XT with a fatty meal or essential fatty acid supplement. Space the doses evenly throughout the day, keeping in mind that the most important time to take a dose is in the late evening. -On cycle, take 2 to 3 capsules per day and follow the optimal dosing guidelines for the duration of the cycle. -On cycle with pre-existing gyno/gyno flare up, take 3 to 4 capsules per day and follow the optimal dosing guidelines for the duration of the cycle. -During PCT, take 2 to 3 capsules per day for at least 4 weeks and follow the optimal dosing guidelines. For the best results, use with Lean Xtreme to control cortisol and its catabolic effects during this transition period. -Off cycle, take 1 to 2 capsules per day in the evening. Who can take it? Rebound XT can be used by men above the age of 18 that are on or off a PH/AAS cycle or during PCT immediately after a cycle. It can be used by any man looking to boost testosterone levels without negatively affecting the body’s natural hormonal balance. What are the possible side effects? Any time there is an increase in testosterone there is a possibility of an increase in oily skin and acne. Over long periods of time, extremely low levels of estrogen can negatively affect cholesterol profile. The body needs some estrogen to maintain the conversion of growth hormone to IGF-1 in the liver. The key is to control estrogen not to eradicate it. Serving Size: 1-3 Tablets Tablets per Container: 60 25mg Tablets
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N.B.O.L.T. Co-founder |
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