BodybuildingForYou - Bodybuilding Forums  

Go Back   BodybuildingForYou - Bodybuilding Forums > Anabolic Steroids, Prohormones, and Testosterone Enhancers > Anabolic Steroids & Anabolic Chemistry & Testosterone Enhancers

Reply
 
LinkBack Thread Tools Display Modes
  #21 (permalink)  
Old 03-08-2004, 04:17 AM
footballfreak's Avatar
footballfreak footballfreak is offline
BB4U Newbie
 
Join Date: Feb 2004
Location: Canada
Posts: 4
footballfreak will become famous soon enough
Default Thourough revisit- making injectables from powders

Test Enanthate 5 gram conversion

Needed
5 grams test E
1ml Benzyl Alcohol = 5% BA
15.25 ml sesame oil
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter


1. Weigh out 5 grams of powder.
2. Place powder in vial.
3. Add BA to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.

Makes 20ml @ 250mg/ml

Test Enanthate 10 gram conversion

Needed
10 grams test E
2ml Benzyl Alcohol = 5% BA
30.5 ml sesame oil
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter


1. Weigh out 10 grams of powder.
2. Place powder in vial.
3. Add BA to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.

Makes 40ml @ 250mg/ml

Test Cypionate 5 gram conversion

Needed
5 grams test c
1ml Benzyl Alcohol = 5% BA
15.25 ml sesame oil
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter


1. Weigh out 5 grams of powder.
2. Place powder in vial.
3. Add BA to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.


Makes 20ml @ 250mg/ml

Test Cypionate 10 gram conversion

Needed
10 grams test c
2ml Benzyl Alcohol = 5% BA
30.5 ml sesame oil
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter


1. Weigh out 10 grams of powder.
2. Place powder in vial.
3. Add BA to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.


Makes 40ml @ 250mg/ml

Equipoise (EQ) for 5 grams of powder (eq is actually liquid at room temp.)

Needed
5 grams EQ
20.50 ml oil
.75 ml Benzyl Alcohol = 3% BA
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter


1. Weigh out 5 grams of powder.
2. Place powder in vial.
3. Add BA to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.

Makes 25ml @ 200mg/ml

Equipoise (EQ) for 10 grams of powder (eq is actually liquid at room temp.)

Needed
10 grams EQ
41 ml oil
1.5 ml Benzyl Alcohol = 3% BA
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter

1. Weigh out 10 grams of powder.
2. Place powder in vial.
3. Add BA to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.

Makes 50ml @ 200mg/ml

1 ml of EQ is 1.18 grams
Grams * 0.85 = ml of Bold Undec to use.

EQ is virtually idiot proof, so I would recommend making all of your product in one sitting if you have more than 5 or 10 grams of EQ, instead of trying to weigh out 5 or 10 grams of it.

Test Prop for 5 grams

Needed
5 grams powder
36.25 ml sesame oil
2.5ml Benzyl Alcohol = 5%
7.5ml Benzyl Benzoate =15%
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter

1. Weigh out 5 grams of powder.
2. Place powder in vial.
3. Add BA & BB to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.

Makes 50 ml @ 100mg/ml

Test Prop for 10 grams

Needed
10 grams powder
72.5 ml sesame oil
5ml Benzyl Alcohol = 5%
15ml Benzyl Benzoate = 15%
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter

1. Weigh out 10 grams of powder.
2. Place powder in vial.
3. Add BA & BB to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.

Makes 100 ml @ 100mg/ml

Deca for 5 grams

5 grams powder
18.75ml sesame oil
1.25ml BA 5%
1.25ml BB 5%
Syringes
Vial
Sterile Vial
Whatman sterile filter

1. Weigh out 5 grams of powder.
2. Place powder in vial.
3. Add BA & BB to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though whatman filter.
10. Take other syringe with 2ml oil, run through whatman into solution.

Makes 25 ml @ 200 mg/ml

Deca for 10 grams

10 grams powder
37.5 ml sesame oil
2.5ml BA 5%
2.5ml BB 5%
Syringes
Vial
Sterile Vial
Whatman sterile filter

1. Weigh out 10 grams of powder.
2. Place powder in vial.
3. Add BA & BB to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though whatman filter.
10. Take other syringe with 2ml oil, run through whatman into solution.

Makes 50 ml @ 200 mg/ml

Tren for 10 grams

Needed
10 grams tren powder
84.5 ml sesame oil
5 ml Benzyl Alcohol = 5%
Syringes 3cc & 5/10cc
18 or 20 gauge needles
mixing Vial
Sterile Vial
Whatman sterile filter

1. Weigh out 10 grams of powder.
2. Place powder in vial.
3. Add BA to the vial.
4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan.
5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial.
6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove.
7. Place a 18 or 20 gauge needle in the sterile vial attach Whatman sterile filter.
8. Place another needle in the sterile vial to relieve the pressure.
9. Draw out solution with a syringe, run though Whatman filter.
10. Take other syringe with 2ml oil, run through Whatman into solution.

Makes 100 ml @ 100mg/ml
Reply With Quote
  #22 (permalink)  
Old 03-08-2004, 04:18 AM
footballfreak's Avatar
footballfreak footballfreak is offline
BB4U Newbie
 
Join Date: Feb 2004
Location: Canada
Posts: 4
footballfreak will become famous soon enough
Default

Would anyone be interested in how to make synthol? This thread is getting a little packed so I won't post it unless there is interest...
Reply With Quote
  #23 (permalink)  
Old 03-08-2004, 07:15 AM
Jason1371 Jason1371 is offline
BB4U Newbie
 
Join Date: Dec 2003
Posts: 17
Jason1371 has a spectacular aura about
Default

Nice posts, the only thing I dont like about posting the long conversion post from MuscleSci, is the fact that the author doesnt use BB, and for alot of new people trying this, they fail to keep it in solution, so keep in mind when doing a conversion, the first few times Id use BB as well to make sure it stays in solution.
http://absinth.greatnow.com/calcpowder2.html - This powder calculator realy helps
Reply With Quote
  #24 (permalink)  
Old 03-21-2004, 09:25 AM
rckpytn's Avatar
rckpytn rckpytn is offline
certified steroidologist
 
Join Date: Jul 2003
Location: Tempe, AZ
Posts: 222
rckpytn is a name known to allrckpytn is a name known to allrckpytn is a name known to all
Send a message via AIM to rckpytn
Default

tren conversion

i converted 4000mg of finaplix with a 4g kit and ended up with a final product of 45ml, that means it is 88.88mg/ml, correct?
__________________
only plants grow naturally
Reply With Quote
  #25 (permalink)  
Old 04-13-2004, 01:56 PM
Jason1371 Jason1371 is offline
BB4U Newbie
 
Join Date: Dec 2003
Posts: 17
Jason1371 has a spectacular aura about
Default

Quote:
Originally Posted by rckpytn
tren conversion

i converted 4000mg of finaplix with a 4g kit and ended up with a final product of 45ml, that means it is 88.88mg/ml, correct?
Roger that.
Reply With Quote
  #26 (permalink)  
Old 04-13-2004, 02:44 PM
rckpytn's Avatar
rckpytn rckpytn is offline
certified steroidologist
 
Join Date: Jul 2003
Location: Tempe, AZ
Posts: 222
rckpytn is a name known to allrckpytn is a name known to allrckpytn is a name known to all
Send a message via AIM to rckpytn
Default

thanks for the late reply, i guess i have been taking 88.8mg ED instead of 75mg ED, maybe that is why i have gained 20 lbs in a little more 3 weeks and i had to go buy new shirts to fit around my arms, it all makes sense now
__________________
only plants grow naturally
Reply With Quote
  #27 (permalink)  
Old 04-14-2004, 07:05 AM
Jason1371 Jason1371 is offline
BB4U Newbie
 
Join Date: Dec 2003
Posts: 17
Jason1371 has a spectacular aura about
Default

Yeah PM me if u need help with any conversions. Ive been in the field latley, im in the marines..So its hard for me to get on here
Reply With Quote
  #28 (permalink)  
Old 04-11-2005, 03:27 PM
batfink69 batfink69 is offline
BB4U Newbie
 
Join Date: Apr 2005
Posts: 1
batfink69 is on a distinguished road
Default

Quote:
Originally Posted by Jason1371
Im gonna go over a few convertions, that most people
This will ensure that all your gear stuck in the filter still is flushed out. Now take out the 18g needle with the filter, and take your new gear with the 25g needle still in, and bake it at 250 degrees for 45 mins!
Let it cool and congrats, you now have 20ml of 250mg/ml Testosterone Enanthate. Its actually about 251mg/ml
You know its legit, sterile, and let me assure u, it will be the most painless injection
When you say to bake at 250 degrees...with pin in...This means the rubber stopper is in the vial...This won't melt?
Reply With Quote
  #29 (permalink)  
Old 04-11-2005, 03:40 PM
Poobah's Avatar
Poobah Poobah is offline
BB4U Super Heavyweight
 
Join Date: Jun 2004
Location: Canada
Posts: 1,158
Poobah is a glorious beacon of lightPoobah is a glorious beacon of light
Default

Yes the rubber stopper is in the vial.. and no it won't melt.

The plastic part of the pin can melt and block the pin if your oven is too hot... so If you want to be extra careful, cut the plastic part off the "vent" pin.
__________________
Pause Squats - 345 x 5, June 6 2006
Deadlift - 505 x 4, June 1 2006
BB Bench - 340 x 1, March 15th 2006

Last edited by Poobah; 04-14-2005 at 04:30 PM.
Reply With Quote
  #30 (permalink)  
Old 08-24-2005, 06:04 PM
salb3039's Avatar
salb3039 salb3039 is offline
Moderator
 
Join Date: Nov 2003
Location: Tennessee
Posts: 54
salb3039 is a name known to allsalb3039 is a name known to all
Send a message via AIM to salb3039 Send a message via Yahoo to salb3039
Default

Anybody know of any other guides to homebrewing out there? Id like to look into this a little more. And if possible links to some of the supplies.
Reply With Quote
  #31 (permalink)  
Old 08-24-2005, 06:19 PM
bulkmuscle bulkmuscle is offline
Banned
 
Join Date: Jun 2004
Posts: 33
bulkmuscle is on a distinguished road
Default

http://www.bulkmuscle.com/forum/index.php?showforum=18
http://anabolicminds.com/forum/forumdisplay.php?f=46
http://anabolicminds.com/forum/forumdisplay.php?f=45

Last edited by bulkmuscle; 08-24-2005 at 06:22 PM.
Reply With Quote
  #32 (permalink)  
Old 08-24-2005, 06:31 PM
salb3039's Avatar
salb3039 salb3039 is offline
Moderator
 
Join Date: Nov 2003
Location: Tennessee
Posts: 54
salb3039 is a name known to allsalb3039 is a name known to all
Send a message via AIM to salb3039 Send a message via Yahoo to salb3039
Default

Sweet! Thanks.
Reply With Quote
  #33 (permalink)  
Old 10-23-2005, 02:19 PM
superman8791's Avatar
superman8791 superman8791 is offline
BB4U Newbie
 
Join Date: Dec 2004
Location: Smallville
Posts: 1
superman8791 is on a distinguished road
Default

Man you guys are a riot! Makin your own gear. Freakin Chemist Genius!!!
Reply With Quote
  #34 (permalink)  
Old 11-09-2005, 10:41 AM
Poobah's Avatar
Poobah Poobah is offline
BB4U Super Heavyweight
 
Join Date: Jun 2004
Location: Canada
Posts: 1,158
Poobah is a glorious beacon of lightPoobah is a glorious beacon of light
Default

Thanks to Twitch

one subject im not to familiar with...
know a usp grade DMSO is better than industrial grade...


little info from BigCat..
CEM

How to make your own local delivery topicals
This is a repost from a post I made elsewhere.

Introduction

The current wave of local delivery topicals is based on the work of Marcel Nimni (Nimni, 1989, Nimni et al, 1997 & 1998) who developed and patented the trans-phase delivery system in 1989. The local delivery of products was reviewed by Guy and Maibach in 1982, and clearly demonstrated a number of products substantially increased localized subcutaneous concentrations of topically applied products. The products that best succeeded in doing this were those that were amphiphillic, that means they are soluble in both water and organic solvents (alcohols and oils for example).

Nimni's idea was simple : make the compound that needs to be delivered stable and amphiphillic and you can get substantial local delivery, with very minimal systemic delivery. This gives a predominantly localized effect, with minimum systemic (side-)effects. As research has previously demonstrated, benzyl alcohol can form micelles with organic ingredients, like most drugs used, in an aqueous environment. That means if you dissolve the products in benzyl alcohol you form an amphiphillic complex that can pass the skin and is taken up locally in the subcutaneous tissue to a great extent. Simply using benzyl alcohol and your product would already allow for local delivery, especially since benzyl is also a good penetrant of the skin due to its amphiphillic properties. But Nimni's system consisted of two phases. The second phase being a mixture of acetone and isopropanol. Both these solvents are very volatile and have both been shown to enhance skin permeation (Onken and Moyer, 1963). The idea is that the acetone and isopropanol make the skin more permeable and then evaporate, creating a sort of funneling effect that leaves the product entirely dissolved in the less volatile benzyl alcohol, which forms the amphiphillic micelles and carries the product across the skin. It transfers as it were, from one phase to another, and hence was dubbed the trans-phase delivery system by Nimni and his associates (Nimni et al, 1997).

Here are some good tips for people wanting to try this :

- All the ingredients, contrary to the current line of products using this technology are very cheap and very easy to get at any drugstore.

- The current line of products does not use acetone, even though research shows it to be the better product. they only use isopropanol. Using both however will create a much better and more stable effect. Nimni's idea was to use the two products with different evaporation rates to create more of a funneling effect whereby the acetone evaporates, leaving product funneled in a mixture of isopropanol and benzyl and then shortly after the isopropanol evaporates leaving it all in the benzyl.

How to make your own TPDS :

Take the product you wish to deliver, then add benzyl alcohol until it is entirely dissolved, even a few drops more (adequate benzyl for product). Then add a mixture of 4 parts acetone and 5 parts isopropanol, until you get the volume that gives you the desired concentration of drug per ml, and then apply as many ml as necessary to the site of application, twice daily.

Penetration enhancement

The rate limiting step, believe it or not, is still the permeation through the skin. The rate limiting step for that is permeation through the outer most layer, the stratum corneum. The stratum corneum can be depicted, for functional purposes, as a brick wall. The cells, called corneocytes, are the bricks, and in between is a continuous lipid layer that represents the mortar. Whether you traverse the stratum corneum through or between the cells, your penetration enhancers shoudl always exert an effect on the lipid layer. Almost all known permeation enhancers, with the exception of DMSO, work solely on the lipid layer. So that should not be a problem.

Here comes the tricky part, and another were manufacturers of existing products have fumbled a great deal. Penetration enhancers that do not evaporate (like acetone and isopropanol) also traverse the skin. They also dissolve organic compounds very well. That means if you volume of penetration enhancers is to great, a great deal of your product will traverse the skin dissolved in your permeation enhancer instead of in the benzyl micelles, and will be taken up systemic. Making all your efforts fruitless and rendering your product nothing more than a more expensive transdermal product. So when selecting permeation enhancers, select those that have the most effect in the smallest known volume. That is one area where most current products drop the ball.

Occlusion : the contradiction

Occlusion is often used with percutaneous absorption, whether it be local or transdermal, and has been shown to increase penetration of the skin. At first it was believed that this occured through the increase of water in the skin, but increased water was shown to have a minimal effect on lipid disorder in the lipid layers of the stratum corneum (Suhonen et al, 1999), so most likely it is a combination of both increased hydration and increased heat together, with either factor being relatively irrelevant alone.

The contradiction however is that occlusion is not an option with TPDS, since it would prevent evaporation of the first phase, resulting in part of the first phase traversing the skin, with product dissolved, resulting in systemic and not local delivery

This is yet another reason for an extremely small volume of penetration enhancers. If you cannot accomodate this, then it is best not to use PE's at all, as Nimni himself did, rather than risk affecting your primary delivery system.

Why Skulpt didn't work, but how you can make it work in your favour

Skulpt was an analog that was released for a while and then pulled again, that attempted to compete with aforementioned products, but despite all the obvious flaws in said products, failed at doing so.

The idea behind it was to use DMSO as a carrier instead of benzyl alcohol. DMSO is an incredibly potent penetration enhancer that affects both the lipid layers and the structure of the cells in between. It is also amphiphillic and easily builds up in subcutaneous tissues in high concentrations, and a good solvent for most organic compounds. So what was the problem ? Well, apparently DMSO does not function as a carrier. Instead it traverses the skin first and then pulls the product through, so to speak (kurihara-Bergstromm et al, 1987). Which is why skulpt failed.

Using a smaller dose of DMSO with the TPDS would also fail. First of all, when using DMSO as a solvent you need at least 50% for it to work adequately, while even 5% would already be enough to prevent TPDS from working properly. It traverses the skin and is a good solvent, so most of the product would dissolve in the DMSO and be lost systemically, rather than delivered locally through funneling to the benzyl phase.

Using DMSO however would benefit us greatly. Repeated application of percutaneous products results in less and less uptake with each use, and this occurs mostly through resistance in the lipid layers (Barry et all, 1972). So using a product that also works on the cells would definitely attenuate this decrease much much longer.

So how can we use DMSO ? Well the same researchers that found DMSO did not function as a carrier also tested an assymetrical model where they applied the DMSO first, and then the product. This resulted in a notably enhanced uptake of the compound WITH LESS DMSO THAN WHEN USING IT AS A SOLVENT. That means if you pretreat the skin with DMSO, and then apply your TPDS 5-10 minutes later, you have effectively created a product that blows any existing product out of the water.

But because you need less DMSO, and still have better and longer working penetration because of it, and don't require any of the large volume penetration enhancers often used, that screw up TPDS delivery, you save even more money (less DMSO, no other PE's and cheap TPDS in drug store) and get a much greater effect (DMSO stronger PE, TPDS works better).

Considering it was the PE's (and possibly greed) that made these initial formula's so extremely expensive, and that skulpt was also extremely expensive because of the high dose and high quality DMSO (you can choose for yourself now what quality DMSO you like) and both delivered relatively poor results, its basically a win-win situation.

Conclusion

You can no effectively make a local delivery formula in your kitchen that is ten times more effective, and ten times cheaper than any existing formula, and on top of that it allows you to look for cheaper ingredients, ingredients or combinations thereof that you deem more fit, or ingredients that couldn't be legally used by supplement companies.

And trust me, the inquisitive mind can easily improve on even this formula 5-10 times

Enjoy all homebrewers ...
__________________
Pause Squats - 345 x 5, June 6 2006
Deadlift - 505 x 4, June 1 2006
BB Bench - 340 x 1, March 15th 2006
Reply With Quote
  #35 (permalink)  
Old 01-06-2006, 06:33 PM
longhorn_7's Avatar
longhorn_7 longhorn_7 is offline
BB4U Newbie
 
Join Date: Dec 2005
Location: wisconsin
Posts: 8
longhorn_7 is on a distinguished road
Default

poobs you took steriods? and i thought you just used whey and all that jazz thats not cool at all. i thought you just used hard work and determination
Reply With Quote
  #36 (permalink)  
Old 01-06-2006, 06:52 PM
Poobah's Avatar
Poobah Poobah is offline
BB4U Super Heavyweight
 
Join Date: Jun 2004
Location: Canada
Posts: 1,158
Poobah is a glorious beacon of lightPoobah is a glorious beacon of light
Default

Quote:
Originally Posted by longhorn_7
poobs you took steriods? and i thought you just used whey and all that jazz thats not cool at all. i thought you just used hard work and determination
This ain't the place for but yes...

But don't think I didn't loose alot and make alot of ground before I did anything... I lost 80 pounds and made tremendous gains before I ever used eca or anything considered a fat burner... And I didn't use steroids till I lost over 100 pounds, and put a good base on naturally.

And During all the natural time, I got up at 4:30am 5 days a week minimum and walked, and eventually jogged, and jogged longer.. at the 5:00am around the street of the city I live in.... And then went to work... and since the very beginning, I've been hitting the iron hard aswell.

Does that make steroids right.. no it don't. But It's what I wanted to do, and I'm going to continue.

peace.
__________________
Pause Squats - 345 x 5, June 6 2006
Deadlift - 505 x 4, June 1 2006
BB Bench - 340 x 1, March 15th 2006
Reply With Quote
  #37 (permalink)  
Old 04-22-2006, 11:46 PM
boxer2007 boxer2007 is offline
BB4U Newbie
 
Join Date: Jan 2006
Posts: 13
boxer2007 is on a distinguished road
Default

Wonder why? Maybe because its a FELONY in many places

Last edited by RRAdam; 04-23-2006 at 12:41 AM.
Reply With Quote
  #38 (permalink)  
Old 04-23-2006, 12:01 AM
t_dot_porkchop's Avatar
t_dot_porkchop t_dot_porkchop is offline
Moderator
 
Join Date: Jul 2003
Location: Toronto
Posts: 651
t_dot_porkchop is a name known to allt_dot_porkchop is a name known to all
Default

Sorry porky, but I felt it necessary.

Last edited by RRAdam; 04-23-2006 at 12:42 AM.
Reply With Quote
  #39 (permalink)  
Old 05-04-2006, 08:11 PM
just1pilot just1pilot is offline
BB4U Newbie
 
Join Date: May 2006
Posts: 1
just1pilot is on a distinguished road
Default how to find a good site

hey JASON 1371 you seem like you know a lot i have been making my own fina for a while now. Found this product called phinaderm its a lotion u mix powders with. Like DSMO only better i guess. wondering if you have heard anything about it. Also i have found out about getting powders online from china bought it twice now and been burned stuff was fake. waste of 300 dollars any tips on how to find a reliable source should i even be messing around with that china stuff i heard it suppose to be good if you can get the real thing.
Reply With Quote
  #40 (permalink)  
Old 08-11-2006, 12:48 AM
Merk0135's Avatar
Merk0135 Merk0135 is offline
BB4U Super Heavyweight
 
Join Date: Jul 2006
Posts: 2,652
Merk0135 has much to be proud ofMerk0135 has much to be proud ofMerk0135 has much to be proud ofMerk0135 has much to be proud ofMerk0135 has much to be proud ofMerk0135 has much to be proud ofMerk0135 has much to be proud ofMerk0135 has much to be proud of
Default

Holy chit this is confusing, lol. I don't even know where to begin with half this stuff. I've never been around it and the terminology might as well be in greek.
Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are On



All times are GMT -6. The time now is 10:30 PM.


Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2010, Jelsoft Enterprises Ltd.
SEO by vBSEO 3.0.0 ©2007, Crawlability, Inc.